Tuulonen A, Airaksinen J, Schwartz B, Alanko H I, Juvala P A
Department of Ophthalmology, University of Oulu, Finland.
Ophthalmology. 1992 Jul;99(7):1111-6. doi: 10.1016/s0161-6420(92)31843-3.
The purpose of this study is to examine the differences between measurements of neuroretinal rim area of the optic disc defined by configuration and by pallor.
One hundred seventy-one patients were studied (59 with glaucoma, 96 ocular hypertensive patients, and 16 controls). The magnification-corrected neuroretinal rim area was measured from black-and-white stereoscopic paper prints. The central area of pallor was measured using computer-assisted image analysis techniques. The percentage of central area of pallor was converted into mm2, and an estimate of neuroretinal rim area defined by color was calculated.
The correlation between the measurements of neuroretinal rim area by configuration and by pallor was statistically highly significant (r = 0.89, P less than 0.0001). No consistent differences between measurements were found in different diagnostic groups, or in different stages or types of glaucomatous optic disc abnormality. The correlation of changes of both measurements during a 9-year follow-up period also was statistically significant (r = 0.68, P less than 0.001).
In clinical routine measurements of the neuroretinal rim area, using both configuration and pallor definition does not seem to add to the information.
本研究旨在探讨通过形态和色泽界定的视盘神经视网膜边缘区域测量值之间的差异。
对171例患者进行了研究（59例青光眼患者、96例高眼压症患者和16例对照）。从黑白立体纸质打印件上测量经放大校正后的神经视网膜边缘区域。使用计算机辅助图像分析技术测量色泽中央区。将色泽中央区的百分比换算为平方毫米，并计算出由颜色界定的神经视网膜边缘区域的估计值。
通过形态和色泽测量的神经视网膜边缘区域之间的相关性在统计学上具有高度显著性（r = 0.89，P < 0.0001）。在不同诊断组、不同阶段或不同类型的青光眼性视盘异常中，测量值之间未发现一致的差异。在9年随访期内，两种测量值变化的相关性在统计学上也具有显著性（r = 0.68，P < 0.001）。
在临床常规测量神经视网膜边缘区域时，同时使用形态和色泽界定似乎并未增加更多信息。
