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[Anxiolytic effect of dehydroepiandrosterone sulfate in male mice with high anxiety level].

作者信息

Ovsiukova M V, Amikishieva A V, Kudriavtseva N N, Obut T A

机构信息

Institute of Physiology, Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, Novosibirsk.

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 2003 Nov-Dec;53(6):789-93.

Abstract

Effects of dehydroepiandrosterone sulfate (DHEAS, 30 mg/kg, i.p., 4 and 28 hours after an injection) on CBA/Lac male mice with increased level of anxiety resulting from chronic (20-day) social confrontations were studied in two behavioral tests. The anxiolytic effect of DHEAS was observed both 4 and 28 hours after an injection in the partition test of social interactions and in the plus-maze test.

摘要

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