[食管癌切除标本的收缩]

[Shrinkage of resected specimens of esophageal carcinoma].

作者信息

Ma Guo-Wei, Rong Tie-Hua, Long Hao, Fu Jian-Hua, Lin Peng, Huang Zhi-Fan, Zeng Can-Guang, Zhang Xu, Li Xiao-Dong, Zhang Lan-Jun, Wen Zhe-Sheng, Wang Jun-Ye, Zhang Peng-Yuan, Hu Yi, Zhu Zhi-Hua

机构信息

Department of Thoracic Surgery, Cancer Center, Sun Yat-Sen University, Guangzhou, Guangdong, PR China.

出版信息

Ai Zheng. 2004 Feb;23(2):193-5.

PMID:14960243

Abstract

BACKGROUND & OBJECTIVE: There are some kinds of shrinkage in resected specimens of esophageal carcinoma; however,there were few reports on its regularity. This study was designed to investigate the degree of shrinkage in resected specimens of esophageal carcinoma.

METHODS

Specimens of seventy patients with esophageal squamous cell carcinoma who underwent resections in Cancer Center, Sun Yat-Sen University were collected. The length of the upper margin,the tumor,and the lower margin were measured with a ruler during operation before the esophagus was removed (in situ). After the esophagus was removed, the specimens were cut longitudinally on the side opposite the tumor, then the length of the upper margin, the tumor, and the lower margin were measured again without retraction. After 48 h fixation of 10% formalin (fixed), the length of the upper margin, the tumor, and the lower margin were measured again.

RESULTS

After resection,the shrinkage rates of the upper margin, the tumor,and the lower margin were (40.71+/-10.02)%,(83.59+/-16.57)%, and (58.41+/-12.03)% of their in situ length; after 48 h fixation of 10% formalin, the shrinkage rates of the upper margin,the tumor, and the lower margin were (40.06+/-10.50)%, (80.92+/-15.88)%, and (54.83+/-11.29)% of their in situ length (P< 0.05).

CONCLUSION

The specimens of esophageal carcinoma shrink remarkably after removed and after formalin fixation.

摘要

背景与目的

食管癌切除标本存在多种收缩情况；然而，关于其规律的报道较少。本研究旨在探讨食管癌切除标本的收缩程度。

方法

收集中山大学肿瘤防治中心70例行食管癌切除术的食管鳞状细胞癌患者的标本。在切除食管前（原位）手术过程中，用尺子测量食管上切缘、肿瘤及下切缘的长度。食管切除后，在肿瘤对侧纵行切开标本，然后在不牵拉的情况下再次测量上切缘、肿瘤及下切缘的长度。用10%甲醛固定48小时后（固定后），再次测量上切缘、肿瘤及下切缘的长度。

结果

切除后，上切缘、肿瘤及下切缘的收缩率分别为其原位长度的(40.71±10.02)%、(83.59±16.57)%和(58.41±12.03)%；用10%甲醛固定48小时后，上切缘、肿瘤及下切缘的收缩率分别为其原位长度的(40.06±10.50)%、(80.92±15.88)%和(54.83±11.29)%（P<0.05）。