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[γ射线辐照对孕鼠及其胚胎肝脏核基质蛋白生物合成的影响]

[Effects of gamma irradiation on biosynthesis of nuclear matrix proteins of the liver in pregnant rats and their embryos].

作者信息

Mirkhamidova P, Shamsutdinova G T, Mirakhmedov A K, Filatova L S, Bul'diaeva T V, Zbarskiĭ I B

出版信息

Radiobiologiia. 1992 May-Jun;32(3):406-11.

PMID:1496112
Abstract

A study was made of the incorporation of 35S-methionine into nuclear matrix proteins of hepatic cells of pregnant rats and their embryos subjected to single gamma-irradiation (60Co, 1 and 2 Gy, 0.0233 Gy/s) on days 3, 13 and 17 of pregnancy and embryogenesis. On day 21 of pregnancy and embryogenesis a decrease in the rate of incorporation of 35S-methionine into nuclear matrix proteins was shown to be a function of radiation dose and time of pregnancy and embryogenesis on the moment of exposure.

摘要

对怀孕大鼠及其胚胎的肝细胞进行研究,这些胚胎在怀孕和胚胎发育的第3天、第13天和第17天接受单次γ射线照射(60Co,1和2 Gy,0.0233 Gy/s),研究35S-甲硫氨酸掺入核基质蛋白的情况。在怀孕和胚胎发育的第21天,结果显示35S-甲硫氨酸掺入核基质蛋白的速率降低是辐射剂量以及照射时怀孕和胚胎发育时间的函数。

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Radiobiologiia. 1992 May-Jun;32(3):406-11.
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