Campolmi P, Sertoli A, Fabbri P, Panconesi E
Contact Dermatitis. 1978 Apr;4(2):93-102. doi: 10.1111/j.1600-0536.1978.tb03741.x.
A case of occupational chrysanthemum contact dermatitis is reported. Patch tests showed the patient to be sensitized to Chrysanthemum morifolium (Chr M) leaves, flowers, and stems (alcoholic extracts) and to alantolactone. An attempt at desensitization appears to have been successful. Gas chromatography indicated the presence of alantolactone in all the various parts of Chr M, mostly in the flowers. The "maximization test" succeeded in sensitizing guinea pigs to alantolactone.
报告了一例职业性菊花接触性皮炎病例。斑贴试验表明,该患者对菊花(Chr M)的叶子、花朵和茎(酒精提取物)以及土木香内酯过敏。脱敏尝试似乎取得了成功。气相色谱分析表明,土木香内酯存在于菊花的各个部位,主要存在于花朵中。“最大化试验”成功使豚鼠对土木香内酯产生了过敏反应。