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颅咽管瘤手术后的炎性血栓栓塞并发症?

Inflammatory thromboembolic complication after craniopharyngioma surgery?

作者信息

Fischer B, Palkovic S, Schildheuer D, Heindel W, Wassmann H

机构信息

Department of Neurosurgery, University of Muenster, Muenster, Germany.

出版信息

Acta Neurochir (Wien). 2004 Feb;146(2):183-6. doi: 10.1007/s00701-003-0178-z. Epub 2003 Dec 22.

Abstract

Aside from endocrine or visual disturbances an appearance of other complications after craniopharyngioma surgery is rare. We report a case of delayed brain infarction in the postoperative period of craniopharyngioma resection. A 30-year-old man presented with visual impairment and diabetes insipidus. Imaging revealed a partly cystic, partly contrast enhancing intra-/suprasellar mass lesion. The patient underwent craniotomy with resection of the tumour. Histological examination revealed an adamantinomatous craniopharyngioma. Early postoperative an aseptic meningitis, which was diagnosed clinically as well as by laboratory and CSF analysis, resolved spontaneously. One week later a cerebral incident with infarction in the peripheral territory of MCA on the left side occurred. For this unusual event with a review of the literature a thromboembolic origin is suggested on the basis of inflammatory vascular involvement after an attack of aseptic meningitis.

摘要

除了内分泌或视觉障碍外,颅咽管瘤手术后出现其他并发症的情况很少见。我们报告一例颅咽管瘤切除术后延迟性脑梗死病例。一名30岁男性出现视力障碍和尿崩症。影像学检查发现鞍内/鞍上有部分囊性、部分强化的肿块病变。患者接受了开颅肿瘤切除术。组织学检查显示为造釉细胞瘤型颅咽管瘤。术后早期发生无菌性脑膜炎,经临床、实验室及脑脊液分析确诊,后自行缓解。一周后,左侧大脑中动脉外周区域发生梗死性脑事件。基于无菌性脑膜炎发作后炎症性血管受累,结合文献复习,提示这一不寻常事件为血栓栓塞性起源。

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