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体育锻炼神经内分泌反应的潜在机制。

Mechanisms underlying the neuroendocrine response to physical exercise.

作者信息

Leal-Cerro A, Gippini A, Amaya M J, Lage M, Mato J A, Dieguez C, Casanueva F F

机构信息

Division of Endocrinology, Virgen del Rocio Hospital, Sevilla, Spain.

出版信息

J Endocrinol Invest. 2003 Sep;26(9):879-85. doi: 10.1007/BF03345239.

DOI:10.1007/BF03345239
PMID:14964441
Abstract

Exercise initiates a coordinated series of physiological responses, including hypothalamic-pituitary-adrenal (HPA) axis and sympathetic nervous system activation, that, in combination, lead to the appropriate selection and utilization of metabolic substrates. Physical activity acts as a powerful stimulus for the hypothalamic-pituitary axis, leading to the liberation of several neuroendocrine hormones. The nature of this stimulation varies according to the kind of exercise (intensity, duration, aerobic, strength) and subject characteristics (gender, previous training), as well as depending on the time of the day and meal ingestion. As a whole, the neuroendocrine responses to exercise represent an accurate regulator of fuels (glucose, free fatty acids) homeostasis in a special situation characterized by a drastic increase of the energy requirements at muscle level. In this article the current knowledge about this topic is reviewed.

摘要

运动引发一系列协调的生理反应,包括下丘脑 - 垂体 - 肾上腺(HPA)轴和交感神经系统的激活,这些反应共同导致代谢底物的适当选择和利用。身体活动是下丘脑 - 垂体轴的强大刺激因素,导致几种神经内分泌激素的释放。这种刺激的性质因运动类型(强度、持续时间、有氧运动、力量训练)、个体特征(性别、既往训练情况)而异,还取决于一天中的时间和进餐情况。总体而言,运动引起的神经内分泌反应是在肌肉水平能量需求急剧增加这一特殊情况下,对燃料(葡萄糖、游离脂肪酸)稳态的精确调节。本文对该主题的当前知识进行了综述。

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本文引用的文献

1
Hormonal responses to daily strenuous walking during 4 successive days.连续4天每日进行剧烈步行后的激素反应。
Eur J Appl Physiol. 2002 Nov;88(1-2):122-7. doi: 10.1007/s00421-002-0689-y. Epub 2002 Aug 27.
2
Effect of long-term strength training on glucose metabolism. Implications for individual impact of high lean mass and high fat mass on relationship between BMI and insulin sensitivity.长期力量训练对葡萄糖代谢的影响。高瘦体重和高脂肪量对体重指数与胰岛素敏感性之间关系的个体影响的意义。
J Endocrinol Invest. 2002 Jun;25(6):520-5. doi: 10.1007/BF03345494.
3
The role of leptin in reproduction: experimental and clinical aspects.
J Neurosci Res. 2022 Aug;100(8):1602-1642. doi: 10.1002/jnr.24990. Epub 2021 Dec 1.
4
Possible Neuroprotective Mechanisms of Physical Exercise in Neurodegeneration.运动对神经退行性变的神经保护作用机制。
Int J Mol Sci. 2020 Aug 16;21(16):5895. doi: 10.3390/ijms21165895.
5
Hypothalamic /, Plasmatic Glucose and Lactate Remain Unchanged During Habituation to Forced Exercise.在适应强迫运动的过程中,下丘脑、血浆葡萄糖和乳酸水平保持不变。
Front Physiol. 2020 May 15;11:410. doi: 10.3389/fphys.2020.00410. eCollection 2020.
6
Exercise training and physiological responses to acute stress: study protocol and methodological considerations of a randomised controlled trial.运动训练与对急性应激的生理反应:一项随机对照试验的研究方案及方法学考量
BMJ Open Sport Exerc Med. 2018 Aug 21;4(1):e000393. doi: 10.1136/bmjsem-2018-000393. eCollection 2018.
7
Carbohydrate-Restriction with High-Intensity Interval Training: An Optimal Combination for Treating Metabolic Diseases?碳水化合物限制与高强度间歇训练:治疗代谢性疾病的最佳组合?
Front Nutr. 2017 Oct 12;4:49. doi: 10.3389/fnut.2017.00049. eCollection 2017.
8
The Cortisol Awakening Response in Patients with Poststroke Depression Is Blunted and Negatively Correlated with Depressive Mood.中风后抑郁症患者的皮质醇觉醒反应减弱,且与抑郁情绪呈负相关。
Biomed Res Int. 2015;2015:709230. doi: 10.1155/2015/709230. Epub 2015 Aug 31.
9
Using biofeedback while immersed in a stressful videogame increases the effectiveness of stress management skills in soldiers.在沉浸于紧张的电子游戏时使用生物反馈,可提高士兵的应激管理技能的效果。
PLoS One. 2012;7(4):e36169. doi: 10.1371/journal.pone.0036169. Epub 2012 Apr 27.
10
Transcriptional control of complement activation in an exercise model of chronic fatigue syndrome.慢性疲劳综合征运动模型中补体激活的转录调控
Mol Med. 2009 Jan-Feb;15(1-2):34-42. doi: 10.2119/molmed.2008.00098. Epub 2008 Nov 10.
瘦素在生殖中的作用:实验与临床方面。
Ann Med. 2002;34(1):5-18. doi: 10.1080/078538902317338599.
4
Gender governs the relationship between exercise intensity and growth hormone release in young adults.性别决定了年轻人运动强度与生长激素释放之间的关系。
J Appl Physiol (1985). 2002 May;92(5):2053-60. doi: 10.1152/japplphysiol.01018.2001.
5
Influence of prolonged continuous exercise on hormone responses to subsequent exercise in humans.长时间持续运动对人体后续运动激素反应的影响。
Eur J Appl Physiol. 2001 Oct;85(6):578-85. doi: 10.1007/s004210100498.
6
Evidence for a causal role of low energy availability in the induction of menstrual cycle disturbances during strenuous exercise training.在剧烈运动训练期间,低能量可利用性在诱发月经周期紊乱中起因果作用的证据。
J Clin Endocrinol Metab. 2001 Nov;86(11):5184-93. doi: 10.1210/jcem.86.11.8024.
7
Effect of hydration on exercise-induced growth hormone response.
Eur J Endocrinol. 2001 Oct;145(4):445-50. doi: 10.1530/eje.0.1450445.
8
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9
Cortisol and growth hormone responses to exercise at different times of day.皮质醇和生长激素在一天中不同时间对运动的反应。
J Clin Endocrinol Metab. 2001 Jun;86(6):2881-9. doi: 10.1210/jcem.86.6.7566.
10
Hormonal responses to high- and moderate-intensity strength exercise.对高强度和中等强度力量训练的激素反应。
Eur J Appl Physiol. 2000 May;82(1-2):121-8. doi: 10.1007/s004210050661.