Francois Monique E, Gillen Jenna B, Little Jonathan P
University of British Columbia Okanagan, Kelowna, BC, Canada.
University of Toronto, Toronto, ON, Canada.
Front Nutr. 2017 Oct 12;4:49. doi: 10.3389/fnut.2017.00049. eCollection 2017.
Lifestyle interventions incorporating both diet and exercise strategies remain cornerstone therapies for treating metabolic disease. Carbohydrate-restriction and high-intensity interval training (HIIT) have independently been shown to improve cardiovascular and metabolic health. Carbohydrate-restriction reduces postprandial hyperglycemia, thereby limiting potential deleterious metabolic and cardiovascular consequences of excessive glucose excursions. Additionally, carbohydrate-restriction has been shown to improve body composition and blood lipids. The benefits of exercise for improving insulin sensitivity are well known. In this regard, HIIT has been shown to rapidly improve glucose control, endothelial function, and cardiorespiratory fitness. Here, we report the available evidence for each strategy and speculate that the combination of carbohydrate-restriction and HIIT will synergistically maximize the benefits of both approaches. We hypothesize that this lifestyle strategy represents an optimal intervention to treat metabolic disease; however, further research is warranted in order to harness the potential benefits of carbohydrate-restriction and HIIT for improving cardiometabolic health.
结合饮食和运动策略的生活方式干预仍然是治疗代谢性疾病的基础疗法。限制碳水化合物摄入和高强度间歇训练（HIIT）已分别被证明可改善心血管和代谢健康。限制碳水化合物摄入可降低餐后高血糖，从而限制过度血糖波动可能产生的有害代谢和心血管后果。此外，限制碳水化合物摄入已被证明可改善身体成分和血脂。运动对改善胰岛素敏感性的益处是众所周知的。在这方面，高强度间歇训练已被证明可迅速改善血糖控制、内皮功能和心肺适能。在此，我们报告了每种策略的现有证据，并推测限制碳水化合物摄入和高强度间歇训练的结合将协同最大化两种方法的益处。我们假设这种生活方式策略是治疗代谢性疾病的最佳干预措施；然而，为了利用限制碳水化合物摄入和高强度间歇训练对改善心脏代谢健康的潜在益处，仍需进一步研究。
