Solky Benjamin A, Pincus Laura, Horan Richard F
Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Cutis. 2004 Jan;73(1):65-7.
Vancomycin-induced linear IgA bullous dermatosis (LABD) previously has been described; however, past reports have suggested that the clinical presentation is nonspecific. We present a case of vancomycin-induced LABD with a suggestive clinical presentation; specifically, groups of annularly arranged vesicles. We propose that this clinical presentation strongly suggests drug-induced LABD and should raise a clinician's suspicion of vancomycin as the offending agent. This awareness may guide the antibiotic management of the patient while the clinician awaits histopathologic correlation.
先前已有关于万古霉素诱导的线状 IgA 大疱性皮肤病（LABD）的描述；然而，过去的报告表明其临床表现缺乏特异性。我们报告一例具有提示性临床表现的万古霉素诱导的 LABD 病例；具体表现为成组的环形排列水疱。我们认为这种临床表现强烈提示药物性 LABD，应引起临床医生对万古霉素作为致病药物的怀疑。这种认识可在临床医生等待组织病理学相关结果时指导患者的抗生素管理。
