阿魏对阴道毛滴虫的体外作用。

The in vitro effect of Assafoetida on Trichomonas vaginalis.

作者信息

Ramadan Nashwa I, Al Khadrawy Faisal M

机构信息

Department of Parasitology, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt.

出版信息

J Egypt Soc Parasitol. 2003 Aug;33(2):615-30.

PMID:14964671

Abstract

Assafoetida is an oleo-gum resin obtained from the roots and stems of many Ferula species such as F. foetida Regel, F. asafoetida Linn, F. alliacea Boiss. and F. narthex Boiss, family Umbelliferae (carrot family), plants growing indigenously in Iran, Afghanistan and north of India. Assafoetida is commonly used as a flavoring agent in food and as a traditional medicine for many diseases in many parts of the world. In this work, the effect of Assafoetida on growth of Trichomonas vaginalis in vitro was studied and compared to metronidazole as a reference drug. It showed that Assafoetida had a potent antiparasitic effect on T. vaginalis compared to metronidazole, thus, worth further investigation to study its applicability in treatment of parasitic infections.

摘要

阿魏是一种油胶树脂，取自多种阿魏属植物的根和茎，如臭阿魏（Ferula foetida Regel）、阿魏（Ferula asafoetida Linn）、蒜叶阿魏（Ferula alliacea Boiss.）和纳尔特克斯阿魏（Ferula narthex Boiss），属于伞形科（胡萝卜科），这些植物原产于伊朗、阿富汗和印度北部。在世界许多地方，阿魏通常用作食品调味剂和治疗多种疾病的传统药物。在这项研究中，研究了阿魏对阴道毛滴虫体外生长的影响，并与作为参考药物的甲硝唑进行了比较。结果表明，与甲硝唑相比，阿魏对阴道毛滴虫具有强大的抗寄生虫作用，因此，值得进一步研究以探讨其在治疗寄生虫感染中的适用性。