Ambrose Catherine G, Clanton Thomas Oscar
Department of Orthopedic Surgery, The University of Texas Health Science Center at Houston, TX 77030, USA.
Ann Biomed Eng. 2004 Jan;32(1):171-7. doi: 10.1023/b:abme.0000007802.59936.fc.
Bioabsorbable implants are widely used in orthopedic surgery today and the worldwide market is expanding rapidly. Despite the popularity of these implants, reports of complications continue to appear in the literature. Although the complications rarely have an adverse affect on long-term outcomes, the reports are too numerous to be mere isolated incidents related to one specific implant. Complications have been reported with most of the commercially available implant materials with varying incidence rates and severities of reactions to the implants. The purpose of this review is to summarize the adverse events that have been reported in clinical trials of bioabsorbable implants in orthopedic surgery.
生物可吸收植入物如今在骨科手术中被广泛使用,全球市场正在迅速扩张。尽管这些植入物很受欢迎,但文献中仍不断出现并发症的报告。虽然这些并发症很少对长期预后产生不利影响,但报告数量众多,不太可能只是与一种特定植入物相关的孤立事件。大多数市售植入物材料都有并发症报告,对植入物的反应发生率和严重程度各不相同。本综述的目的是总结骨科手术中生物可吸收植入物临床试验中报告的不良事件。