严重低钙血症中的横向白甲症。
Transverse leukonychia in severe hypocalcemia.
作者信息
Foti Caterina, Cassano Nicoletta, Palmieri Vincenzo O, Portincasa Piero, Conserva Anna, Lamuraglia Michele, Palasciano Giuseppe, Vena Gino A
机构信息
Unit of Dermatology, Department of Internal Medicine, Immunology and Infectious Diseases, University of Bari, Italy.
出版信息
Eur J Dermatol. 2004 Jan-Feb;14(1):67-8.
We report the case of a 26-year-old man with acral tetany and muscular cramps of the upper limbs associated with hypocalcemia caused by hypoparathyroidism and celiac disease. Physical examination revealed a transverse leukonychia which disappeared after treatment with calcium lactogluconate, calcium carbonate and calcitriol. Hypocalcemia may induce nail alterations with a double mechanism represented by angiospasm and disorganization of the hard keratin and of the integrin subunits.
我们报告了一例26岁男性病例，其患有手足搐搦和上肢肌肉痉挛，与甲状旁腺功能减退和乳糜泻引起的低钙血症相关。体格检查发现有横行白甲，经葡萄糖酸钙、碳酸钙和骨化三醇治疗后消失。低钙血症可能通过血管痉挛以及硬角蛋白和整合素亚基紊乱这两种机制导致指甲改变。
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