血液净化对慢性肾衰竭患者血浆中完整甲状旁腺激素水平的影响。
Effect of blood purification on plasma levels of intact parathyroid hormone in patients with chronic renal failure.
作者信息
Liu Jun, Liu Zhi-qiang, Tao Hui-qin
机构信息
Department of Nephrology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.
出版信息
Di Yi Jun Yi Da Xue Xue Bao. 2004 Feb;24(2):234-5.
OBJECTIVE
To study the effects of hemoperfusion and/or hemodialysis on plasma levels of intact parathyroid hormone (iPTH) in patients with chronic renal failure (CRF).
METHODS
A total of 40 uremic patients were randomly divided into two groups to receive hemoperfusion in combination with hemodialysis (HP+HD) or exclusive hemodialysis (HD), respectively. Plasma iPTH concentration was measured by means of radio immunoassay.
RESULTS
After the blood purification procedures, the patients' plasma iPTH levels were reduced from 1,508.70+/-1,268.89 to 1,049.04+/-992.91 microg/ml (P<0.001) in HD group and from 1,600.70+/-1,151.15 to 745.47+/-785.02 microg/ml (P<0.001) in HP+HD group.
CONCLUSION
Blood purification with hemoperfusion plus hemodialysis may decrease plasma iPTH levels more efficiently than hemodialysis performed alone.
目的
研究血液灌流和/或血液透析对慢性肾衰竭（CRF）患者血浆全段甲状旁腺激素（iPTH）水平的影响。
方法
40例尿毒症患者随机分为两组，分别接受血液灌流联合血液透析（HP+HD）或单纯血液透析（HD）治疗。采用放射免疫分析法测定血浆iPTH浓度。
结果
血液净化治疗后，HD组患者血浆iPTH水平从1,508.70±1,268.89降至1,049.04±992.91μg/ml（P<0.001），HP+HD组从1,600.70±1,151.15降至745.47±785.02μg/ml（P<0.001）。
结论
血液灌流联合血液透析进行血液净化比单纯血液透析能更有效地降低血浆iPTH水平。
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