Stauber Martin, Huber Martin, Van Lenthe G Harry, Boyd Steven K, Müller Ralph
Institute for Biomedical Engineering, Swiss Federal Institute of technology and University of Zürich, Zürich, Switzerland.
Comput Methods Biomech Biomed Engin. 2004 Feb;7(1):9-16. doi: 10.1080/10255840410001656408.
This paper presents a new method for the generation of a beam finite element (FE) model from a three-dimensional (3D) data set acquired by micro-computed tomography (micro-CT). This method differs from classical modeling of trabecular bone because it models a specific sample only and differs from conventional solid hexahedron element-based FE approaches in its computational efficiency. The stress-strain curve, characterizing global mechanical properties of a porous structure, could be well predicted (R(2)=0.92). Furthermore, validation of the method was achieved by comparing local displacements of element nodes with the displacements directly measured by time-lapsed imaging methods of failure, and these measures were in good agreement. The presented model is a first step in modeling specific samples for efficient strength analysis by FE modeling. We believe that with upcoming high-resolution in-vivo imaging methods, this approach could lead to a novel and accurate tool in the risk assessment for osteoporotic fractures.
本文提出了一种从微计算机断层扫描(micro-CT)获取的三维(3D)数据集中生成梁有限元(FE)模型的新方法。该方法不同于小梁骨的经典建模,因为它仅对特定样本进行建模,并且在计算效率方面不同于传统的基于实体六面体单元的有限元方法。表征多孔结构整体力学性能的应力-应变曲线能够得到很好的预测(R(2)=0.92)。此外,通过将单元节点的局部位移与通过失效的延时成像方法直接测量的位移进行比较,实现了该方法的验证,并且这些测量结果吻合良好。所提出的模型是通过有限元建模对特定样本进行高效强度分析建模的第一步。我们相信,随着即将出现的高分辨率体内成像方法,这种方法可能会成为骨质疏松性骨折风险评估中一种新颖且准确的工具。