Poelert Sander, Valstar Edward, Weinans Harrie, Zadpoor Amir A
Department of Biomechanical Engineering, Faculty of Mechanical, Maritime, and Materials Engineering, Delft University of Technology (TU Delft), Delft, The Netherlands.
Proc Inst Mech Eng H. 2013 Apr;227(4):464-78. doi: 10.1177/0954411912467884. Epub 2012 Dec 27.
Finite element modeling is an engineering tool for structural analysis that has been used for many years to assess the relationship between load transfer and bone morphology and to optimize the design and fixation of orthopedic implants. Due to recent developments in finite element model generation, for example, improved computed tomography imaging quality, improved segmentation algorithms, and faster computers, the accuracy of finite element modeling has increased vastly and finite element models simulating the anatomy and properties of an individual patient can be constructed. Such so-called patient-specific finite element models are potentially valuable tools for orthopedic surgeons in fracture risk assessment or pre- and intraoperative planning of implant placement. The aim of this article is to provide a critical overview of current themes in patient-specific finite element modeling of bones. In addition, the state-of-the-art in patient-specific modeling of bones is compared with the requirements for a clinically applicable patient-specific finite element method, and judgment is passed on the feasibility of application of patient-specific finite element modeling as a part of clinical orthopedic routine. It is concluded that further development in certain aspects of patient-specific finite element modeling are needed before finite element modeling can be used as a routine clinical tool.
有限元建模是一种用于结构分析的工程工具，多年来一直被用于评估载荷传递与骨形态之间的关系，以及优化骨科植入物的设计与固定。由于有限元模型生成方面的最新进展，例如，计算机断层扫描成像质量的提高、分割算法的改进以及计算机速度的加快，有限元建模的准确性大幅提高，并且可以构建模拟个体患者解剖结构和特性的有限元模型。这种所谓的患者特异性有限元模型对于骨科医生进行骨折风险评估或植入物放置的术前和术中规划而言，是潜在的有价值工具。本文旨在对骨骼患者特异性有限元建模的当前主题进行批判性综述。此外，将骨骼患者特异性建模的最新技术水平与临床适用的患者特异性有限元方法的要求进行比较，并对患者特异性有限元建模作为临床骨科常规一部分应用的可行性作出判断。得出的结论是，在有限元建模能够用作常规临床工具之前，需要在患者特异性有限元建模的某些方面进一步发展。
