Chen Tie-lou, Lin Shi-long, Liu Guo-qin, Liu Jing-chang, Song Pei-zhi, Xu Bing, Zhang Xin-hai, Wang Gang, Chen Jun
Department of Periodontology, Stomatological Research Center of Naval Hospital 411, Shanghai 200081.
Shanghai Kou Qiang Yi Xue. 2003 Dec;12(6):403-5.
This paper studied the therapeutic effects and holding time of hyperbaric oxygen (HBO) on human severe periodontitis.
30 cases with periodontitis were selected and randomly divided into 2 groups, i.e. the HBO group and control group. For HBO group, they were exposed to a pressure of 0.25 MPa. For control group, they were rinsed with gargle. Gingival indices (GI), sulcus bleeding indices (SBI), plaque index (PLI), probing depth (PD), attachment loss (AL) and gingival crevicular fluid (GCF) were measured during both the first and last clinical visits, and 1 year after HBO therapy. The gingival blood flow (GBF) were measured by Laser Doppler Flowmeter.
HBO can decrease GI of patients with periodontitis by 1.1 decrease SBI by 1.2, lower PD and AL by 0.7 mm, decrease the volume of GCF by 2.0, and significant differences could be seen in the above indices between pre and post HBO therapy. The GBF had a 1.8 folds increase after HBO exposure. GI and SBI one year after HBO therapy were larger than that of the time after HBO therapy. There were no significant differences in the PLI, PD, AL, GCF, GBF between post HBO therapy and 1 year after HBO therapy.
HBO had good therapeutic effects on human severe periodontitis, the effects can keep more than 1 year.
研究高压氧（HBO）对人类重度牙周炎的治疗效果及维持时间。
选取30例牙周炎患者，随机分为两组，即HBO组和对照组。HBO组患者接受0.25MPa的压力治疗。对照组患者进行漱口冲洗。在首次和末次临床就诊时以及HBO治疗后1年，测量牙龈指数（GI）、龈沟出血指数（SBI）、菌斑指数（PLI）、探诊深度（PD）、附着丧失（AL）和龈沟液（GCF）。用激光多普勒血流仪测量牙龈血流量（GBF）。
HBO可使牙周炎患者的GI降低1.1，SBI降低1.2，PD和AL降低0.7mm，GCF量降低2.0，HBO治疗前后上述指标有显著差异。HBO治疗后GBF增加了1.8倍。HBO治疗1年后的GI和SBI大于HBO治疗后的水平。HBO治疗后与治疗后1年的PLI、PD、AL、GCF、GBF无显著差异。
HBO对人类重度牙周炎有良好的治疗效果，且效果可维持1年以上。
