Smeenk Jesper M J, Verhaak Christianne M, Stolwijk Annette M, Kremer Jan A M, Braat Didi D M
Department of Obstetrics and Gynaecology, University Medical Center Radboud, Nijmegen, The Netherlands.
Fertil Steril. 2004 Feb;81(2):262-8. doi: 10.1016/j.fertnstert.2003.09.027.
To gain more insight into psychological aspects of dropping out from IVF-ICSI.
Prospective cohort study.
University hospital-based tertiary care fertility clinic.
PATIENT(S): Women entering their first treatment cycle of IVF or ICSI.
INTERVENTION(S): Standardized psychological questionnaires were administered before the start of the treatment and after treatment.
MAIN OUTCOME MEASURE(S): Reasons for dropout, state and trait anxiety, depression, and marital and sexual satisfaction.
RESULT(S): Baseline psychological factors and the probability of dropout after IVF-ICSI treatment were found to be associated in the group that stopped treatment for psychological reasons. Those who were denied further treatment by the medical team, the "actively censored" group, did not show pretreatment differences regarding psychological measures in comparison with those who continued treatment. After treatment, the group that was denied further treatment showed higher levels of anxiety and depression compared with those that continued.
CONCLUSION(S): Dropout, being a well-known phenomenon in IVF-ICSI, is related to preexisting psychological factors in IVF-ICSI. Actively censored patients were psychologically well-adjusted before treatment, but this changed after censoring.
更深入了解体外受精-卵胞浆内单精子注射（IVF-ICSI）治疗中断的心理因素。
前瞻性队列研究。
大学医院附属三级护理生育诊所。
进入首次IVF或ICSI治疗周期的女性。
在治疗开始前和治疗后进行标准化心理问卷调查。
治疗中断的原因、状态焦虑和特质焦虑、抑郁以及婚姻和性满意度。
在因心理原因停止治疗的组中，发现基线心理因素与IVF-ICSI治疗后的治疗中断概率相关。被医疗团队拒绝进一步治疗的患者，即“主动被审查”组，与继续治疗的患者相比，在心理测量方面未显示出治疗前差异。治疗后，被拒绝进一步治疗的组与继续治疗的组相比，焦虑和抑郁水平更高。
治疗中断是IVF-ICSI中一个众所周知的现象，与IVF-ICSI中预先存在的心理因素有关。主动被审查的患者在治疗前心理适应良好，但在被审查后情况发生了变化。
