Oyster R, Leipold H W, Troyer D, Cash W, Johnson D
Department of Veterinary Diagnosis, College of Veterinary Medicine, Kansas State University, Manhattan 66506.
Zentralbl Veterinarmed A. 1992 Jun;39(5):321-7. doi: 10.1111/j.1439-0442.1992.tb00189.x.
Histochemical and morphometric analysis of selected skeletal muscles was performed on 14 pure bred, Brown Swiss cattle. Nine cattle were clinically affected with bovine progressive degenerative myeloencephalopathy (BPDME) while five served as controls. Statistically significant trend differences were not observed for the parameters of mean cross sectional area, and mean fiber type percentages for types, I, IIA, and IIB fibers between affected and control test groups. In general, patterns of hypertrophy or atrophy, fiber type grouping, fiber type predominance, or fiber cross sectional profile alteration were not observed in the muscles examined from affected cattle. The findings suggest that BPDME, or weaver syndrome, is not a muscular dystrophy and that muscle pathology is not a primary part of the syndrome nor would muscle pathology be expected to contribute significantly to the clinical signs of the disease.
对14头纯种瑞士褐牛的选定骨骼肌进行了组织化学和形态计量学分析。9头牛临床上患有牛进行性退行性脊髓脑病（BPDME），5头作为对照。在受影响和对照测试组之间，I型、IIA型和IIB型纤维的平均横截面积和平均纤维类型百分比参数未观察到统计学上的显著趋势差异。一般来说，在受影响牛的检查肌肉中未观察到肥大或萎缩模式、纤维类型分组、纤维类型优势或纤维横截面积轮廓改变。研究结果表明，BPDME或韦弗综合征不是肌肉营养不良症，肌肉病理学不是该综合征的主要部分，也预计肌肉病理学不会对该疾病的临床症状有显著影响。
