Braun U, Ehrensperger F, Bracher V
Tierarztl Prax. 1987;15(2):139-44.
The clinical signs and pathological lesions, consistent with Bovine Progressive Degenerative Myeloencephalopathy (BPDME), are described in a heifer. The animal was an 18-month-old Braunvieh-/Brown Swiss crossbreed with 50% Brown Swiss. Both the sire as well as the dam were related to the bull "B.". The only neurological signs were a posterior ataxia. Mobility and coordination of the front legs were normal. The CK activity of the cerebrospinal fluid was enhanced. There was a moderate to severe degeneration of the white matter consisting of marked axonal degradation and distension and degradation of myelin sheats in all parts of the spinal cord as well as in the medulla oblongata. The lesions were more severe in the descending than in the ascending tracts.
一头小母牛出现了与牛进行性退行性脊髓脑病变（BPDME）相符的临床症状和病理损伤。这头动物是一头18个月大的布劳恩维厄牛/瑞士褐牛杂交种，含有50%的瑞士褐牛血统。其父系和母系均与公牛“B”有亲缘关系。唯一的神经学症状是后部共济失调。前肢的活动能力和协调性正常。脑脊液中的肌酸激酶活性增强。白质出现中度至重度退化，表现为脊髓和延髓各部位明显的轴突降解、肿胀以及髓鞘降解。下行束的病变比上行束更严重。
