Łastowska Lucyna, Jabłecka Anna
Pol Merkur Lekarski. 2003 Nov;15(89):399-401.
Gene therapy is one of the challenges in the medicine. The advance, which had been achieved in a molecular biology through last ten years, brought to the first clinical trials of gene therapy. This treatment method may find a big application in cardiology, for example: cardiomyopathy, restenosis and ischaemic heart disease. The main problem in the gene therapy is to supply a therapeutic gene to target cell of the patient and to express it. Clinical effectiveness of the gene therapy has not been proved yet so, therefore it is necessary to carry out more new designed researches, which would enable to accept the gene therapy as an effective treatment. Using the gene therapy beside social and ethic problems gives a lot of law's doubts.
基因治疗是医学领域的挑战之一。过去十年分子生物学取得的进展推动了基因治疗的首次临床试验。这种治疗方法可能在心脏病学中得到广泛应用，例如：心肌病、再狭窄和缺血性心脏病。基因治疗的主要问题是将治疗性基因输送到患者的靶细胞并使其表达。基因治疗的临床有效性尚未得到证实，因此有必要开展更多新设计的研究，以使基因治疗被认可为一种有效的治疗方法。除了社会和伦理问题外，基因治疗的使用还引发了许多法律上的疑问。
