French B A
University of Louisville, Department of Medicine, KY 40202, USA.
Curr Opin Cardiol. 1998 May;13(3):205-13.
This article provides the cardiologist with an overview of recent basic research relevant to the application of somatic cell gene therapy against cardiovascular disease. Somatic cell gene therapy simply refers to the use of genes as medicine, but this is a potent form of medicine that will bring major advances to nearly every form of medical practice. In the field of cardiology, research suggests that gene therapy may find application against nearly every form of cardiovascular disease. Although it is not possible to review every advance in the field, this article does provide an overview of some of the gene therapy approaches currently being pursued against atherosclerosis, thrombosis, restenosis, myocardial infarction, hypertension, heart failure, and transplant rejection.
本文为心脏病专家概述了近期与体细胞基因疗法治疗心血管疾病应用相关的基础研究。体细胞基因疗法简单来说就是将基因用作药物，但这是一种强大的药物形式，将给几乎每种医疗实践带来重大进展。在心脏病学领域，研究表明基因疗法可能适用于几乎每种心血管疾病。虽然不可能回顾该领域的每一项进展，但本文确实概述了目前针对动脉粥样硬化、血栓形成、再狭窄、心肌梗死、高血压、心力衰竭和移植排斥反应所采用的一些基因疗法。
