Giroux D, Lapointe G, Baril M
Commission de la santé et de la sécurité du travail (CSST), Montreal, Quebec, Canada.
Am Ind Hyg Assoc J. 1992 Jul;53(7):471-4. doi: 10.1080/15298669291359960.
The increasing number of women in the workplace has made it more important than ever to ensure a safe work environment, particularly with respect to mothers who choose to breast-feed their babies. The Quebec Commission de la santé et de la sécurité du travail (CSST) Toxicological Index is fully involved in the provincial program for the protective reassignment of workers who breast-feed infants. The Infotox database provides peer-reviewed information concerning chemicals identified in the workplace that may appear in the mother's milk, possibly to be ingested by the breast-fed infant. Data extracted from the CSST computer system that holds information on 5,500 substances are presented. A total of 153 chemicals (2.7%) are recognized as being involved in some milk transfer. The strength of evidence is assessed with reference to strong or weak association (excretion or detection) in humans or in animals. Such an effect provides a useful basis for administrative decision involving protective reassignment as well as evaluation of work environment. Database users must be well informed about the identification of chemicals in breast milk because this is an essential step for the evaluation of the hazards of transferring chemicals encountered in the workplace from mother to baby. Actually, the main problem is that there are very few data in the scientific literature concerning milk transfer.
职场中女性数量的不断增加，使得确保安全的工作环境比以往任何时候都更加重要，对于选择母乳喂养婴儿的母亲来说尤其如此。魁北克职业健康与安全委员会（CSST）毒理学索引全面参与了该省针对母乳喂养婴儿的工人进行保护性重新分配的项目。Infotox数据库提供了经过同行评审的信息，这些信息涉及在工作场所中发现的可能会出现在母乳中、进而可能被母乳喂养的婴儿摄入的化学物质。本文展示了从CSST计算机系统中提取的数据，该系统存有5500种物质的信息。共有153种化学物质（占2.7%）被认为与某些乳汁转移有关。证据的强度是根据在人类或动物身上的强关联或弱关联（排泄或检测）来评估的。这种效应为涉及保护性重新分配以及工作环境评估的行政决策提供了有用的依据。数据库用户必须充分了解母乳中化学物质的识别情况，因为这是评估工作场所中遇到的化学物质从母亲转移到婴儿身上所产生危害的关键步骤。实际上，主要问题在于科学文献中关于乳汁转移的数据非常少。
