Garcia C J, Daneman A, Thorner P, Daneman D
Departamento Radiologia, Hospital Clinico Universidad Catolica, Santiago, Chile.
Am J Dis Child. 1992 Jul;146(7):811-6. doi: 10.1001/archpedi.1992.02160190043017.
Multinodular disease of the thyroid gland is uncommon in children and adolescents, and has received little attention in the recent literature. This article reviews the clinical, sonographic, and pathologic findings in 16 children with multinodular disease of the thyroid gland, and draws attention to the high incidence of other associated clinical findings. This condition was associated with a triad including renal and digital anomalies in three patients, with McCune-Albright syndrome in two patients, with Hashimoto's thyroiditis in three patients, and with thyroid carcinoma in four patients. Three of five patients with a history of previous radiation therapy had thyroid carcinoma. Sonography is a proven valuable imaging modality for the study of thyroid disease in children and has contributed to our understanding of multinodular disease of the thyroid gland in this age group.
甲状腺多结节疾病在儿童和青少年中并不常见，且在最近的文献中很少受到关注。本文回顾了16例甲状腺多结节疾病患儿的临床、超声及病理表现，并提请注意其他相关临床表现的高发生率。这种情况与三联征相关，包括3例患者伴有肾脏和手指异常，2例患者伴有McCune-Albright综合征，3例患者伴有桥本甲状腺炎，4例患者伴有甲状腺癌。5例有既往放疗史的患者中有3例患有甲状腺癌。超声检查是研究儿童甲状腺疾病的一种经证实的有价值的影像学方法，有助于我们了解该年龄组的甲状腺多结节疾病。
