Bagger Jens Peder, Hall Roger J C, Koutroulis George, Nihoyannopoulos Petros
Imperial College London, NHLI & Cardiothoracic Directorate, Hammersmith Hospital, London, United Kingdom.
Am J Cardiol. 2004 Feb 15;93(4):465-7. doi: 10.1016/j.amjcard.2003.10.045.
We studied the effect of enhanced external counterpulsation (EECP) in 23 consecutive patients with stable angina pectoris who had a positive dobutamine stress echocardiogram. After EECP, stress-induced wall motion score (WMS) improved by > or =2 grades in 43% of the patients (n = 10); the average improvement was 5.3 +/- 3.8 compared with -0.6 +/- 3.0 in the remaining 13 patients (p = 0.007). The diastolic/systolic augmentation ratio increased by 217% in response to the full course of EECP (p = 0.0002) among patients with improved WMS, and by 71% (p = 0.004) among the other patients; the increase was greater among patients with improved WMS than among patients with no improvement (p = 0.01). After EECP, Canadian Cardiovascular Society angina class improved from 3.1 +/- 0.6 to 2.2 +/- 0.7 (p <0.0001) in the entire group and exercise capacity increased by 73 seconds (p = 0.0002) in patients who were able to exercise (n = 18).
我们研究了增强型体外反搏(EECP)对23例连续的稳定型心绞痛患者的影响,这些患者多巴酚丁胺负荷超声心动图结果呈阳性。EECP治疗后,43%(n = 10)的患者应激诱发的室壁运动评分(WMS)改善≥2级;其余13例患者的平均改善为5.3±3.8,而他们为-0.6±3.0(p = 0.007)。在WMS改善的患者中,EECP全程治疗后舒张期/收缩期增强比值增加217%(p = 0.0002),在其他患者中增加71%(p = 0.004);WMS改善的患者增加幅度大于未改善的患者(p = 0.01)。EECP治疗后,整个组的加拿大心血管学会心绞痛分级从3.1±0.6改善至2.2±0.7(p <0.0001),能够运动的患者(n = 18)运动能力增加73秒(p = 0.0002)。