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增强型体外反搏对严重慢性心绞痛患者多巴酚丁胺诱发的左心室壁运动异常的影响。

Effect of enhanced external counterpulsation on dobutamine-induced left ventricular wall motion abnormalities in severe chronic angina pectoris.

作者信息

Bagger Jens Peder, Hall Roger J C, Koutroulis George, Nihoyannopoulos Petros

机构信息

Imperial College London, NHLI & Cardiothoracic Directorate, Hammersmith Hospital, London, United Kingdom.

出版信息

Am J Cardiol. 2004 Feb 15;93(4):465-7. doi: 10.1016/j.amjcard.2003.10.045.

DOI:10.1016/j.amjcard.2003.10.045
PMID:14969625
Abstract

We studied the effect of enhanced external counterpulsation (EECP) in 23 consecutive patients with stable angina pectoris who had a positive dobutamine stress echocardiogram. After EECP, stress-induced wall motion score (WMS) improved by > or =2 grades in 43% of the patients (n = 10); the average improvement was 5.3 +/- 3.8 compared with -0.6 +/- 3.0 in the remaining 13 patients (p = 0.007). The diastolic/systolic augmentation ratio increased by 217% in response to the full course of EECP (p = 0.0002) among patients with improved WMS, and by 71% (p = 0.004) among the other patients; the increase was greater among patients with improved WMS than among patients with no improvement (p = 0.01). After EECP, Canadian Cardiovascular Society angina class improved from 3.1 +/- 0.6 to 2.2 +/- 0.7 (p <0.0001) in the entire group and exercise capacity increased by 73 seconds (p = 0.0002) in patients who were able to exercise (n = 18).

摘要

我们研究了增强型体外反搏(EECP)对23例连续的稳定型心绞痛患者的影响,这些患者多巴酚丁胺负荷超声心动图结果呈阳性。EECP治疗后,43%(n = 10)的患者应激诱发的室壁运动评分(WMS)改善≥2级;其余13例患者的平均改善为5.3±3.8,而他们为-0.6±3.0(p = 0.007)。在WMS改善的患者中,EECP全程治疗后舒张期/收缩期增强比值增加217%(p = 0.0002),在其他患者中增加71%(p = 0.004);WMS改善的患者增加幅度大于未改善的患者(p = 0.01)。EECP治疗后,整个组的加拿大心血管学会心绞痛分级从3.1±0.6改善至2.2±0.7(p <0.0001),能够运动的患者(n = 18)运动能力增加73秒(p = 0.0002)。

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引用本文的文献

1
Enhanced External Counterpulsation (EECP): An Evidence-Based Analysis.增强型体外反搏(EECP):基于证据的分析。
Ont Health Technol Assess Ser. 2006;6(5):1-70. Epub 2006 Mar 1.
2
Enhanced external counterpulsation in the treatment of chronic refractory angina: a long-term follow-up outcome from the International Enhanced External Counterpulsation Patient Registry.增强型体外反搏治疗慢性顽固性心绞痛:国际增强型体外反搏患者注册研究的长期随访结果
Clin Cardiol. 2008 Apr;31(4):159-64. doi: 10.1002/clc.20117.
3
An update on enhanced external counterpulsation.
增强型体外反搏的最新进展。
Clin Cardiol. 2005 Mar;28(3):115-8. doi: 10.1002/clc.4960280304.
4
Enhanced external counterpulsation does not alter arterial stiffness in patients with angina.增强型体外反搏不会改变心绞痛患者的动脉僵硬度。
Clin Cardiol. 2004 Dec;27(12):689-92. doi: 10.1002/clc.4960271206.