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利用犬源微卫星探针绘制中华貉(Nyctereutes procyonoides procyonoides)和北极狐(Alopex lagopus)基因组的细胞遗传图谱。

Development of a cytogenetic map for the Chinese raccoon dog (Nyctereutes procyonoides procyonoides) and the arctic fox (Alopex lagopus) genomes, using canine-derived microsatellite probes.

作者信息

Szczerbal I, Rogalska-Niznik N, Schelling C, Schläpfer J, Dolf G, Switonski M

机构信息

Department of Genetics and Animal Breeding, August Cieszkowski Agricultural University of Poznan, Poznan, Poland.

出版信息

Cytogenet Genome Res. 2003;102(1-4):267-71. doi: 10.1159/000075761.

Abstract

New chromosomal assignments of canine-derived cosmid clones containing microsatellites to the Chinese raccoon dog and arctic fox genomes are presented in the study. The localizations are in agreement with data obtained from comparative chromosome painting experiments between the dog and arctic fox genomes. However, paracentric inversions have been detected by comparing the loci order in canid karyotypes. The number of physically mapped loci increased to thirty-five both in the Chinese raccoon dog and in the arctic fox. Furthermore, the present status of the cytogenetic map of the Chinese raccoon dog and arctic fox is presented in this study.

摘要

该研究展示了包含微卫星的犬源黏粒克隆在中国貉和北极狐基因组中的新染色体定位。这些定位与从狗和北极狐基因组之间的比较染色体涂染实验获得的数据一致。然而,通过比较犬科动物核型中的基因座顺序,检测到了臂内倒位。在中国貉和北极狐中,物理定位的基因座数量都增加到了35个。此外,本研究还展示了中国貉和北极狐细胞遗传图谱的现状。

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