Hörner K, Drescher B
Institut für Tiermedizin und Tierhygiene, Lehrstuhl für Anatomie und Physiologie, Haustiere.
Anat Histol Embryol. 1992 Jun;21(2):175-86. doi: 10.1111/j.1439-0264.1992.tb00334.x.
The age dependent development of the long bones' diaphyses (humerus, os femoris and os tibiofibulare) was examined macroscopically, morphometrically and histologically using 15 White New Zealand Rabbits (WN) and 15 Chinchilla-Bastard-Experimental-Rabbits (Chbb) in 5 different age groups. The main growth of bone occurs in the first three months of life. The remodelling from juvenile to adult bone began in the period from the 4th-12th week. The different bones show various characteristic remodelling zones for each localization. Until the 12th week the resorption of juvenile bundled bone predominates. Afterwards an increasing bone formation by osteal bone can be observed. The bone growth is terminated between the 17th and 33rd week. The os tibiofibulare in both breeds represents the major part of the compact bone area on the whole cross-section area. Principally the bone-remodelling process proceeds equally in both breeds. Breed dependent differences in the adult bone are seen in the construction of the circumferential lamellae. These are formed considerably more irregularly by the Chbb-rabbits than by the WN-rabbits.
使用15只新西兰白兔(WN)和15只青紫蓝杂种实验兔(Chbb),分5个不同年龄组,对长骨干(肱骨、股骨和胫腓骨)的年龄依赖性发育进行了宏观、形态测量和组织学检查。骨骼的主要生长发生在生命的前三个月。从幼年骨到成年骨的重塑始于第4至12周。不同的骨骼在每个部位都显示出各种特征性的重塑区域。直到第12周,幼年束状骨的吸收占主导。此后,可以观察到骨膜骨形成增加。骨骼生长在第17至33周之间终止。两个品种的胫腓骨在整个横截面积中占密质骨面积的主要部分。原则上,两个品种的骨重塑过程是相同的。成年骨中品种依赖性差异体现在环层板的结构上。Chbb兔形成的环层板比WN兔形成的要明显不规则得多。