Swaim S F, Vaughn D M, Spalding P J, Riddell K P, McGuire J A
Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, AL 36849.
Am J Vet Res. 1992 Jul;53(7):1266-72.
Three configurations of cast padding and no cast padding were evaluated for their effects on skin in dogs. Padding was placed over bony prominences, between bony prominences, and over both areas for full-length padding under short-limb walking casts applied to 1 pelvic limb of Greyhounds. Evaluations were performed by pressure measurement over the calcaneal tuberosity, measurement of skin thromboxane B2 (TxB2) concentrations in skin over bony prominences, and measurement of plasma TxB2 concentrations. Pressure studies were performed to evaluate cutaneous pressures related to no cast padding and various configurations of cast padding. Concentrations of TxB2 in the skin were determined to evaluate the skin inflammatory effects of no padding and the padding configurations, and TxB2 concentrations in the plasma were analyzed to ascertain whether they could be used to predict impending dermal pressure lesions. Flexion of casted limbs revealed the greatest pressure over the calcaneal tuberosity with full-length cast padding. This was followed in decreasing order by no cast padding, padding over the prominences, and padding between the prominences. Compared with all other bony prominences and padding configurations, TxB2 skin concentrations were significantly higher over the calcaneal tuberosity when no padding was used and over the lateral base of metatarsal V when padding was placed between the prominences. Over the calcaneal tuberosity, this was attributed to the sharpness of the prominence and its potential for movement. This high TxB2 concentration corresponded to the high pressure found in the pressure studies. Over the lateral base of metatarsal V, the increase in TxB2 concentration was related to the mass of the prominence and the tendency for localized padding to settle around the area.(ABSTRACT TRUNCATED AT 250 WORDS)
对三种有石膏衬垫和无石膏衬垫的配置进行了评估，以研究它们对犬类皮肤的影响。在灵缇犬一侧后肢短肢行走石膏上，将衬垫放置在骨突上方、骨突之间以及两个区域上方以进行全长衬垫。通过测量跟骨结节处的压力、测量骨突上方皮肤中血栓素B2（TxB2）的浓度以及测量血浆TxB2浓度来进行评估。进行压力研究以评估与无石膏衬垫和各种石膏衬垫配置相关的皮肤压力。测定皮肤中TxB2的浓度以评估无衬垫和衬垫配置对皮肤的炎症影响，并分析血浆中TxB2的浓度以确定它们是否可用于预测即将出现的皮肤压力性损伤。石膏固定肢体的屈曲显示，全长石膏衬垫时跟骨结节处压力最大。其次依次是无石膏衬垫、骨突上方衬垫和骨突之间衬垫，压力逐渐减小。与所有其他骨突和衬垫配置相比，不使用衬垫时跟骨结节处的TxB2皮肤浓度显著更高，而在骨突之间放置衬垫时，第五跖骨外侧基部的TxB2皮肤浓度显著更高。在跟骨结节处，这归因于骨突的尖锐度及其移动可能性。这种高TxB2浓度与压力研究中发现的高压相对应。在第五跖骨外侧基部，TxB2浓度的增加与骨突的大小以及局部衬垫在该区域周围沉降的趋势有关。（摘要截取自250字）
