Arnhold J
Institut für Medizinische Physik und Biophysik, Universität Leipzig, Leipzig, D-04103, Germany.
Biochemistry (Mosc). 2004 Jan;69(1):4-9. doi: 10.1023/b:biry.0000016344.59411.ee.
The heme-containing protein myeloperoxidase is released from stimulated polymorphonuclear leukocytes at sites of inflammation. It is involved in the generation of reactive oxygen and nitrogen species and tissue damage. The general properties and functional aspects of this enzyme are reviewed. Special attention is given to luminescence methods for investigating the release of myeloperoxidase from stimulated cells.
含血红素的蛋白质髓过氧化物酶从炎症部位受刺激的多形核白细胞中释放出来。它参与活性氧和氮物种的生成以及组织损伤。本文综述了这种酶的一般性质和功能方面。特别关注用于研究髓过氧化物酶从受刺激细胞中释放的发光方法。
