Carpenter Scott S, Grillis Michael E
Des Moines University-Osteopathic Medical Center, Des Moines, Iowa, USA.
Curr Surg. 2003 May-Jun;60(3):301-3. doi: 10.1016/S0149-7944(02)00745-6.
This case reports the concomitant findings of carcinoid tumor within a Meckel's diverticulum presenting as an acute abdomen in an adult male. Most Meckel's diverticula remain asymptomatic throughout life, and symptomatic diverticula are virtually nonexistent in older adults. Meckel's diverticulitis is clinically indistinguishable from acute appendicitis, and abnormal or symptomatic diverticula are generally resected. Surgical treatment of Meckel's diverticula is recommended for children during exploration. However, resection is controversial in asymptomatic adults. Carcinoid tumors are the most common primary tumor of the small bowel. The duration of symptoms before diagnosis varies from 2 to 20 years, and half of all patients have incurable abdominal disease at first-look surgery. Metastatic events occur most commonly in the liver with a generally poor prognosis. Surgical resection is the treatment of choice. Both Meckel's diverticula and carcinoid tumor are rare clinical entities, and carcinoid tumors occurring within a Meckel's diverticulum are even more uncommon. Thus, the natural history is difficult to predict and treatment recommendations vary. Solitary, localized, asymptomatic nodules less than 1 cm are generally managed with diverticulectomy or segmental resection. Larger or multiple lesions require wide excision of bowel and mesentery, and hepatic resection may be required for metastatic disease.
本病例报告了一名成年男性患者,梅克尔憩室内的类癌瘤伴发急腹症的相关发现。大多数梅克尔憩室终生无症状,而有症状的憩室在老年人中几乎不存在。梅克尔憩室炎在临床上与急性阑尾炎难以区分,异常或有症状的憩室通常会被切除。对于儿童,建议在探查时对梅克尔憩室进行手术治疗。然而,对于无症状的成年人,是否切除存在争议。类癌瘤是小肠最常见的原发性肿瘤。诊断前症状持续时间从2年到20年不等,半数患者在初次手术时就患有无法治愈的腹部疾病。转移最常发生在肝脏,预后通常较差。手术切除是首选治疗方法。梅克尔憩室和类癌瘤都是罕见的临床病症,而发生在梅克尔憩室内的类癌瘤更为罕见。因此,其自然病程难以预测,治疗建议也各不相同。小于1厘米的孤立、局限、无症状结节通常采用憩室切除术或节段性切除术治疗。较大或多发病变需要广泛切除肠管和肠系膜,对于转移性疾病可能需要进行肝切除。