Caracappa Daniela, Gullà Nino, Lombardo Francesco, Burini Gloria, Castellani Elisa, Boselli Carlo, Gemini Alessandro, Burattini Maria Federica, Covarelli Piero, Noya Giuseppe
General and Oncologic Surgery Unit, Department of Surgical, Radiological and Odontostomatological Sciences, University of Perugia, Perugia, Italy.
World J Surg Oncol. 2014 May 8;12:144. doi: 10.1186/1477-7819-12-144.
Meckel's diverticulum (MD) is the most common congenital anomaly of the gastrointestinal tract and is caused by incomplete obliteration of the vitelline duct during intrauterine life. MD affects less than 2% of the population. In most cases, MD is asymptomatic and the estimated average complication risk of MD carriers, which is inversely proportional to age, ranges between 2% and 4%. The most common MD-related complications are gastrointestinal bleeding, intestinal obstruction and acute phlogosis. Excision is mandatory in the case of symptomatic diverticula regardless of age, while surgical treatment for asymptomatic diverticula remains controversial. According to the majority of studies, the incidental finding of MD in children is an indication for surgical resection, while the management of adults is not yet unanimous. In this case report, we describe the prophylactic resection of an incidentally detected MD, which led to the removal of an occult mucosal carcinoid tumor. In literature, the association of MD and carcinoid tumor is reported as a rare finding. Even though the strategy for adult patients of an incidental finding of MD during surgery performed for other reasons divides the experts, we recommend prophylactic excision in order to avoid any further risk.
梅克尔憩室(MD)是胃肠道最常见的先天性异常,由胎儿期卵黄管未完全闭锁引起。MD在人群中的发病率低于2%。在大多数情况下,MD无症状,MD携带者的估计平均并发症风险与年龄成反比,在2%至4%之间。最常见的与MD相关的并发症是胃肠道出血、肠梗阻和急性炎症。有症状的憩室无论年龄大小均需手术切除,而无症状憩室的手术治疗仍存在争议。根据大多数研究,儿童期偶然发现MD是手术切除的指征,而成年人的处理方式尚未统一。在本病例报告中,我们描述了对偶然发现的MD进行预防性切除,结果发现了一个隐匿性黏膜类癌肿瘤。在文献中,MD与类癌肿瘤的关联被报道为罕见发现。尽管对于因其他原因进行手术时偶然发现MD的成年患者的处理策略存在分歧,但我们建议进行预防性切除以避免任何进一步的风险。