Barqawi Albaha, Gamito Eduard, O'Donnell Colin, Crawford E David
Section of Urologic Oncology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA.
Urology. 2004 Feb;63(2):288-92. doi: 10.1016/j.urology.2003.09.019.
To report the observed usage trend of herbal and vitamin supplements in a population of men visiting a prostate cancer screening clinic and its relation to the Sexual Health Inventory for Men score and the American Urological Association Symptom Score (AUA-SS).
Men participating in the 2001 and 2002 Prostate Cancer Awareness Week screening for prostate cancer were given a self-administered questionnaire. The questions were designed to gather background health information and to determine the use of prescription medications for lower urinary tract symptoms (LUTS), as well as the use of herbal and vitamin supplements. In addition, the AUA-SS and Sexual Health Inventory for Men score were calculated for each participant in the study.
The number of questionnaires completed was 12,457. Of the completed questionnaires, 70% of the participants reported the use of multivitamins, and 21% reported the use of herbal supplements. Ten percent of all men reported the use of prescription medications for LUTS (AUA-SS greater than 15). Of the men reporting the use of prescription medications, 19% were taking finasteride, 17% doxazosin, 20% terazosin, 23% tamsulosin, and 22% other prescription medications. Moreover, the average AUA-SS was greater for the men taking herbs or supplements than for those who did not take herbs or supplements (P <0.001). Nonetheless, the Sexual Health Inventory for Men score did not show a positive correlation between the intake of alternative medications and the severity of erectile dysfunction.
We observed that a substantial proportion of men with LUTS participating in a national prostate cancer screening program were not taking prescription medications for these symptoms. Furthermore, we observed that men taking herbs or vitamin supplements tended to have higher AUA scores. Additional investigation is warranted into the reason some men are not receiving standard prescription medications for LUTS and whether reliance on alternative treatments is playing a role in this phenomenon.
报告在一家前列腺癌筛查诊所就诊的男性群体中观察到的草药和维生素补充剂的使用趋势，及其与男性性健康量表评分和美国泌尿外科学会症状评分（AUA - SS）的关系。
对参加2001年和2002年前列腺癌防治周前列腺癌筛查的男性发放自行填写的问卷。问题旨在收集背景健康信息，确定用于下尿路症状（LUTS）的处方药使用情况，以及草药和维生素补充剂的使用情况。此外，为研究中的每位参与者计算AUA - SS和男性性健康量表评分。
完成的问卷数量为12457份。在完成的问卷中，70%的参与者报告使用多种维生素，21%报告使用草药补充剂。所有男性中有10%报告使用治疗LUTS的处方药（AUA - SS大于15）。在报告使用处方药的男性中，19%服用非那雄胺，17%服用多沙唑嗪，20%服用特拉唑嗪，23%服用坦索罗辛，22%服用其他处方药。此外，服用草药或补充剂的男性的平均AUA - SS高于未服用草药或补充剂的男性（P<0.001）。然而，男性性健康量表评分并未显示替代药物的摄入与勃起功能障碍的严重程度之间存在正相关。
我们观察到，参加全国前列腺癌筛查项目的有LUTS的男性中，很大一部分未针对这些症状服用处方药。此外，我们观察到服用草药或维生素补充剂的男性往往AUA评分更高。有必要进一步调查一些男性未接受LUTS标准处方药治疗的原因，以及对替代疗法的依赖是否在这一现象中起作用。
