McCarney R W, Linde K, Lasserson T J
Department of Psychological Medicine, Imperial College London, Room 4.06, Paterson Centre, 20 South Wharf Road, London, UK, W2 1PD.
Cochrane Database Syst Rev. 2004;2004(1):CD000353. doi: 10.1002/14651858.CD000353.pub2.
Homeopathy involves the use, in dilution, of substances which cause symptoms in their undiluted form. It is one of the most widespread forms of complementary medicines and is also used to treat asthma.
The objective of this review was to assess the effects of homeopathy in people with chronic stable asthma.
We searched the Cochrane Airways Group trials register, the Cochrane Complementary Medicine Field trials register, the Glasgow Homeopathic Hospital database, the Münchener Modell database and reference lists of articles. Searches were current as of August 2003.
Randomised trials of homeopathy for the treatment of stable chronic asthma, with observation periods of at least one week were included.
Data extraction was undertaken by two reviewers. Trial quality was assessed by the reviewers.
Six trials with a total of 556 people were included. These trials were all placebo-controlled and double-blind, but of variable quality. They used different homeopathic treatments which precluded quantitative pooling of results for the primary outcome. Standardised treatments in these trials are unlikely to represent common homeopathic practice, where treatment tends to be individualised. No trial reported a significant difference on validated symptom scales. There were conflicting results in terms of lung function between the studies. There has been only a limited attempt to measure a 'package of care' effect (i.e., the effect of the medication as well as the consultation, which is considered a vital part of individualised homeopathic practice).
REVIEWER'S CONCLUSIONS: There is not enough evidence to reliably assess the possible role of homeopathy in asthma. As well as randomised trials, there is a need for observational data to document the different methods of homeopathic prescribing and how patients respond. This will help to establish to what extent people respond to a 'package of care' rather than the homeopathic intervention alone.
顺势疗法涉及使用稀释后的物质,这些物质在未稀释状态下会引发症状。它是最广泛应用的补充医学形式之一,也用于治疗哮喘。
本综述的目的是评估顺势疗法对慢性稳定型哮喘患者的疗效。
我们检索了Cochrane Airways Group试验注册库、Cochrane补充医学领域试验注册库、格拉斯哥顺势疗法医院数据库、慕尼黑模型数据库以及文章的参考文献列表。检索截至2003年8月。
纳入顺势疗法治疗稳定型慢性哮喘且观察期至少为一周的随机试验。
由两名综述员进行数据提取。综述员对试验质量进行评估。
纳入了6项试验,共556人。这些试验均为安慰剂对照且双盲,但质量参差不齐。它们采用了不同的顺势疗法治疗方法,这使得无法对主要结局的结果进行定量合并。这些试验中的标准化治疗不太可能代表常见的顺势疗法实践,因为顺势疗法治疗往往是个体化的。没有试验报告在经过验证的症状量表上有显著差异。各项研究在肺功能方面的结果相互矛盾。仅有有限的尝试来衡量“一揽子护理”效应(即药物以及咨询的效应,咨询被认为是个体化顺势疗法实践的重要组成部分)。
没有足够的证据来可靠地评估顺势疗法在哮喘中评估顺势疗法的可能作用。除了随机试验外,还需要观察性数据来记录顺势疗法开方的不同方法以及患者的反应。这将有助于确定人们在多大程度上是对“一揽子护理”做出反应,而不仅仅是对顺势疗法干预做出反应。