Sinclair H K, Bond C M, Stead L F
Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Westburn Road, Aberdeen, UK, AB25 2AY.
Cochrane Database Syst Rev. 2004(1):CD003698. doi: 10.1002/14651858.CD003698.pub2.
Smoking cessation is a potentially appropriate role for community pharmacists because they are encouraged to advise on the correct use of nicotine replacement therapy (NRT) products and to provide behavioural support to aid smoking cessation.
This review assessed the effectiveness of interventions by community pharmacy personnel to assist clients to stop smoking.
A search was made of the Cochrane Tobacco Addiction Group database for smoking cessation studies conducted in the community pharmacy setting, using the search terms pharmacist* or pharmacy or pharmacies. Date of the most recent search: March 2003.
Randomized trials which compared interventions by community pharmacy personnel to promote smoking cessation amongst their clients who were smokers compared to usual pharmacy support or any less intensive programme. The main outcome measure was smoking cessation rates at six months or more after the start of the intervention.
Data were extracted by one author and checked by the second, noting: the country of the trial, details of participant community pharmacies, method of subject recruitment, smoking behaviour and characteristics of participants on recruitment, method of randomization, description of the intervention and of any pharmacy personnel training, and the outcome measures. Methodological quality was assessed according to the extent to which the allocation to intervention or control was concealed. Because of the potentially important cluster effects, we also rated trials according to whether they checked for or adjusted for these but, in the absence of consensus on how to pool cluster level data, we adopted a narrative approach to synthesizing the data, rather than a formal meta-analysis.
We identified two trials which met our selection criteria. They included a total of 976 smokers. Both trials were set in the UK and involved a training intervention which included the Stages of Change Model; they then compared a support programme involving counselling and record keeping against a control receiving usual pharmacy support. In both studies a high proportion of intervention and control participants began using NRT. Both studies reported smoking cessation outcomes at three time points. However, the follow-up points were not identical (three, six and 12 months in one, and one, four and nine months in the other), and the trend in abstinence over time was not linear in either study, so the data could not be combined. One study showed a significant difference in self-reported cessation rates at 12 months: 14.3% versus 2.7% (p < 0.001); the other study showed a positive trend at each follow-up with 12.0% versus 7.4% (p = 0.09) at nine months.
REVIEWER'S CONCLUSIONS: The limited number of studies to date suggests that trained community pharmacists, providing a counselling and record keeping support programme for their customers, may have a positive effect on smoking cessation rates. The strength of evidence is limited because only one of the trials showed a statistically significant effect.
戒烟对于社区药剂师而言是一个潜在的合适职责,因为他们被鼓励就正确使用尼古丁替代疗法(NRT)产品提供建议,并提供行为支持以帮助戒烟。
本综述评估了社区药房工作人员协助客户戒烟的干预措施的有效性。
在Cochrane烟草成瘾小组数据库中检索在社区药房环境中进行的戒烟研究,检索词为药剂师*或药房或药店。最近一次检索日期:2003年3月。
随机试验,将社区药房工作人员促进其吸烟客户戒烟的干预措施与常规药房支持或任何强度较低的项目进行比较。主要结局指标是干预开始后六个月或更长时间的戒烟率。
由一位作者提取数据,另一位作者进行核对,记录:试验国家、参与的社区药房详情、受试者招募方法、招募时参与者的吸烟行为和特征、随机化方法、干预措施及任何药房人员培训的描述,以及结局指标。根据干预组或对照组分配的隐藏程度评估方法学质量。由于可能存在重要的聚类效应,我们还根据试验是否检查或调整了这些效应进行评分,但由于在如何汇总聚类水平数据方面缺乏共识,我们采用叙述性方法来综合数据,而不是正式的荟萃分析。
我们确定了两项符合我们入选标准的试验。它们总共纳入了976名吸烟者。两项试验均在英国进行,涉及一项包括改变阶段模型的培训干预;然后将一个包括咨询和记录保存的支持项目与接受常规药房支持的对照组进行比较。在两项研究中,干预组和对照组的参与者中很大一部分开始使用NRT。两项研究均在三个时间点报告了戒烟结果。然而,随访时间点并不相同(一项研究为三个月、六个月和十二个月,另一项为一个月、四个月和九个月),并且两项研究中随着时间推移的戒烟趋势均不是线性的,因此数据无法合并。一项研究显示,在12个月时自我报告的戒烟率有显著差异:14.3% 对2.7%(p < 0.001);另一项研究在每次随访时均显示出积极趋势,九个月时为12.0% 对7.4%(p = 0.09)。
迄今为止的研究数量有限,这表明经过培训为客户提供咨询和记录保存支持项目的社区药剂师可能对戒烟率有积极影响。证据力度有限,因为只有一项试验显示出统计学上的显著效果。