Cox Sharon, Dawkins Lynne, Doshi Jay, Cameron James
London South Bank University, Centre for Addictive Behaviours, School of Applied Sciences, 103 Borough Road, London SE1 0AA, United Kingdom of Great Britain and Northern Ireland.
Grovehill Pharmacy, 2 Henry Wells Square, Hemel Hempstead, England HP2 6BJ, United Kingdom of Great Britain and Northern Ireland.
Addict Behav Rep. 2019 Jul 3;10:100202. doi: 10.1016/j.abrep.2019.100202. eCollection 2019 Dec.
E-cigarettes (EC) are now the most popular quit aid in England but their effectiveness for cessation if offered at a pharmacy has not been tested. Here we test the effectiveness of offering an e-cigarette with and without nicotine replacement therapy (NRT) on 4-6-week quit rates in adult smokers seeking support from a community pharmacy. A between subject, six-week, prospective, cohort design. 115 smokers (female = 74; age = 46.37, = 13.56) chose either an EC, EC + NRT or NRT alone, alongside standard behavioural support. Smokers opting for an EC alone or an EC + NRT were more likely to report complete abstinence from smoking at 4-6 weeks (62.2% and 61.5% respectively) compared to NRT alone (34.8%). An EC intervention was significantly more effective for smoking cessation than NRT in this community pharmacy. The results for e-cigarettes appear positive but with the caveat that participants chose their own products which may have introduced bias.
电子烟（EC）目前是英国最受欢迎的戒烟辅助工具，但在药房提供时其戒烟效果尚未得到测试。在此，我们测试了提供含尼古丁和不含尼古丁替代疗法（NRT）的电子烟对寻求社区药房支持的成年吸烟者4至6周戒烟率的影响。采用受试者间六周前瞻性队列设计。115名吸烟者（女性 = 74名；年龄 = 46.37，标准差 = 13.56）选择了电子烟、电子烟 + NRT或仅NRT，并接受标准行为支持。与仅使用NRT（34.8%）相比，仅选择电子烟或电子烟 + NRT的吸烟者在4至6周时更有可能报告完全戒烟（分别为62.2%和61.5%）。在该社区药房，电子烟干预在戒烟方面比NRT显著更有效。电子烟的结果似乎是积极的，但需注意的是，参与者自行选择产品可能会引入偏差。
