La Viola Marco, Greco Antonio, Mazzoccoli Gianluigi, Carughi Stefano, Puzzolante Felice, De Cata Angelo, Giuliani Antonio, Camagna Antonio
Dipartimento di Medicina Interna, IRCCS Casa Sollievo della Sofferenza, Opera di Padre Pio da Pietrelcina, S. Giovanni Rotondo.
Recenti Prog Med. 2003 Dec;94(12):549-53.
Subclinical hypothyroidism is characterized by normal serum levels of free thyroxine and triiodothyronine with increased serum levels of thyroid-stimulating hormone (TSH) without symptoms. We evaluated by thoracic electrical bioimpedance cardiography the hemodynamic pattern of 38 patients with subclinical hypothyroidism, before and after 6-month therapy with levo(L)-thyroxine. We have not evidenced statistically significant differences for cardiac index, cardiac frequency and vascular peripheral resistances. TSH levels were decreased in a statistically significant way. Results obtained in our study show that hemodynamic pattern is not changed after hormone therapy in patients affected by subclinical hypothyroidism.
亚临床甲状腺功能减退的特征是血清游离甲状腺素和三碘甲状腺原氨酸水平正常,促甲状腺激素(TSH)血清水平升高且无症状。我们通过胸部电阻抗心动描记术评估了38例亚临床甲状腺功能减退患者在接受左甲状腺素治疗6个月前后的血流动力学模式。我们没有发现心脏指数、心率和外周血管阻力有统计学上的显著差异。TSH水平有统计学意义的下降。我们研究中获得的结果表明,亚临床甲状腺功能减退患者接受激素治疗后血流动力学模式没有改变。