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计算机断层扫描测量骨密度(作者译)

[Bone density measurements by computer tomography (author's transl)].

作者信息

Lange S, Weiss T h, Gahl G, Golde G

出版信息

Rofo. 1978 Jul;129(1):66-9. doi: 10.1055/s-0029-1230964.

Abstract

The suitability of the E.M.I. mark I computer scanner for carrying out bone densitometry has been tested, using the forearm. Within the region of interest there was an almost linear relationship between CT densities and the concentration of the bone equivalent substance K2HPO4. By means of a special computer programme, the spongiosa and cortex of both forearm bones could be analysed quantitatively. The reproducibility of the results (coefficient of variation 5%) was similar to that of other procedures in current use. The advantage of the method lies in the fact that it is possible to estimate the spongiosa and cortex separately. Investigations on patients with normal bones have shown that senile demineralisation affects the cortex most severely. On the other hand, in renal osteopathies of chronically dialysed patients, demineralisation in the forearm predominantly involves the spongiosa.

摘要

已使用前臂对E.M.I. Mark I型计算机扫描仪进行骨密度测定的适用性进行了测试。在感兴趣区域内,CT密度与骨等效物质K2HPO4的浓度之间存在几乎线性的关系。通过一个特殊的计算机程序,可以对双侧前臂骨的松质骨和皮质骨进行定量分析。结果的可重复性(变异系数5%)与目前使用的其他方法相似。该方法的优点在于可以分别估计松质骨和皮质骨。对骨骼正常的患者进行的研究表明,老年性脱矿对皮质骨影响最为严重。另一方面,在长期透析患者的肾性骨病中,前臂的脱矿主要累及松质骨。

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