Arsenescu Cătălina, Butcovan Doina, Rotar M, Georgescu G I
School of Medicine, Medical Cardiology-Cardiology Center, University of Medicine and Pharmacy Gr.T. Popa, Iaşi.
Rev Med Chir Soc Med Nat Iasi. 2002 Oct-Dec;106(4):812-6.
It is presented the case of a fifty years old women, diagnosed 3 years ago with systemic lupus erythematosus, under therapy with prednisone and cyclophosphamid therapy. She was admitted in our hospital for right decompensated heart disease and the presence of an apical right ventricular mass occluding part of the right ventricular cavity. The endomyocardial biopsy was made to clearify the nature of this mass. After processing the specimen, the histological study evidenciated an organizing apical thrombotic mass formed in a large right ventricular cavity in conditions of pulmonary hypertention. There are presented data concerning the adverse effects of the systemic lupus erythematosus drug therapy, as well. In these circumstances, we demonstrated histologically, that both conditions could alter the heart morphology.
本文介绍了一位50岁女性的病例，她3年前被诊断为系统性红斑狼疮，接受泼尼松和环磷酰胺治疗。她因右心功能不全和右心室心尖部有一肿块阻塞部分右心室腔而入住我院。进行心内膜心肌活检以明确该肿块的性质。对标本进行处理后，组织学研究显示在肺动脉高压情况下，一个大的右心室腔内形成了一个机化的心尖部血栓性肿块。文中还给出了关于系统性红斑狼疮药物治疗不良反应的数据。在这种情况下，我们通过组织学证明，这两种情况都可能改变心脏形态。
