Torres-Estrada José Luis, Rodríguez Mario H
Centro de Investigación de Paludismo, Instituto Nacional de Salud Pública (INSP), 4a Avenida norte y 19 poniente, colonia Centro, 30700 Tapachula, Chiapas, México.
Salud Publica Mex. 2003 Nov-Dec;45(6):497-505.
Disease vector female mosquitoes respond to physic-chemical signals to localize vertebrate hosts for blood meals. Zoophylic mosquitoes preferentially respond to CO2 and octenol released in the breath and bodily fluids, while anthropophylic mosquitoes respond to lactic acid and a variety of sweat compounds. These compounds are modified by saprophytic microorganisms in the skin sebaceous glands. Other factors present in human dwellings contribute to the integration of microsystems with characteristic odors that have different attraction for mosquitoes, explaining the focalization of malaria transmission in few households in endemic areas. The identification of the chemical attractants and their molecular receptors could be used to complement new methods to attract mosquitoes to traps during epidemiological surveys, to increase their contact with insecticides in control interventions, and for genetic manipulation to divert mosquito bites towards other animal populations. The English version of this paper is available at:http://www.insp.mx/salud/index.html.
病媒雌蚊通过对物理化学信号作出反应来定位脊椎动物宿主以获取血餐。嗜动物血的蚊子优先对呼吸和体液中释放的二氧化碳和辛烯醇作出反应，而嗜人血的蚊子则对乳酸和多种汗液化合物作出反应。这些化合物会被皮肤皮脂腺中的腐生微生物改变。人类住所中存在的其他因素有助于将微系统与具有不同蚊子吸引力的特征气味整合在一起，这解释了疟疾传播在流行地区少数家庭中的集中现象。鉴定化学引诱剂及其分子受体可用于补充新方法，以便在流行病学调查期间将蚊子吸引到诱捕器中，在控制干预措施中增加它们与杀虫剂的接触，并用于基因操作，使蚊子叮咬转向其他动物种群。本文的英文版本可在以下网址获取：http://www.insp.mx/salud/index.html。
