Wade Carol R, Reith Kristine K, Sikora JoAnn Hoffman, Augustine Sharon M
Department of Heart and Lung Transplantation, University of Maryland Medical System, 22 S Greene St, Baltimore, MD 21201, USA.
Crit Care Nurs Q. 2004 Jan-Mar;27(1):17-28; quiz 29-30. doi: 10.1097/00002727-200401000-00003.
While considerable progress is being made in the medical management of heart failure, mortality for this disease process continues to be significant. Cardiac transplantation becomes the treatment of choice for those with end-stage diseases that are acceptable candidates. While care of the cardiac transplant patient is similar to those recovering from cardiopulmonary bypass after sternotomy there are several issues unique to the cardiac transplant recipient. These include cardiac denervation, allograft dysfunction, management of arrhythmias, rejection, immunosuppression, and infectious complications. This article provides an overview of the postoperative management of the cardiac transplant recipient while in the intensive care unit. Additionally, a brief description of the surgical techniques employed and the physiology related to cardiac denervation are presented.
虽然在心力衰竭的药物治疗方面取得了显著进展,但这种疾病的死亡率仍然很高。心脏移植成为那些患有终末期疾病且符合条件的患者的首选治疗方法。虽然心脏移植患者的护理与胸骨切开术后从体外循环恢复的患者相似,但心脏移植受者有几个独特的问题。这些问题包括心脏去神经支配、同种异体移植功能障碍、心律失常的管理、排斥反应、免疫抑制和感染并发症。本文概述了心脏移植受者在重症监护病房的术后管理。此外,还简要介绍了所采用的手术技术以及与心脏去神经支配相关的生理学知识。