Hamann Ingo, Gleich Otto, Klump Georg M, Kittel Malte C, Strutz Jürgen
ENT-Department, University of Regensburg, Franz-Josef-Strauss-Allee 11, 93042 Regensburg, Germany.
J Assoc Res Otolaryngol. 2004 Mar;5(1):49-57. doi: 10.1007/s10162-003-3041-2. Epub 2003 Oct 16.
Gap detection using broadband noise was characterized in a group of young gerbils from the breeding colony of the University of Regensburg (RB gerbils), old RB gerbils, and old gerbils from the breeding colony of the University of South Carolina (SC gerbils). Data from old RB and old SC gerbils were not significantly different and were subsequently combined for a comparison with data from the group of young RB gerbils. Level dependence of gap-detection thresholds in young and old domesticated gerbils resembled the typical mammalian pattern of level dependence. Gap-detection thresholds of old gerbils were significantly elevated at 30 dB SL and 50 dB SPL as compared with young gerbils. Compared with young gerbils tested at 30 dB SL and 50 dB SPL, the distribution of gap-detection thresholds in old gerbils was broader with a spread to higher gap-detection thresholds. Some old animals retained excellent temporal resolution, while some showed impaired gap detection. The gap-detection data collected in young and old gerbils resemble previously published data from humans of different age and confirm that gerbils are a useful model to study age-dependent changes in temporal processing.
利用宽带噪声进行的间隙检测，在雷根斯堡大学繁殖群体中的一组年轻沙鼠（RB沙鼠）、年老RB沙鼠以及南卡罗来纳大学繁殖群体中的年老沙鼠（SC沙鼠）中得到了表征。来自年老RB沙鼠和年老SC沙鼠的数据没有显著差异，随后将它们合并起来与年轻RB沙鼠组的数据进行比较。年轻和年老家养沙鼠间隙检测阈值的强度依赖性类似于典型的哺乳动物强度依赖性模式。与年轻沙鼠相比，年老沙鼠在30 dB SL和50 dB SPL时的间隙检测阈值显著升高。与在30 dB SL和50 dB SPL下测试的年轻沙鼠相比，年老沙鼠间隙检测阈值的分布更宽，且向更高的间隙检测阈值扩展。一些老年动物保持了出色的时间分辨率，而一些则表现出间隙检测受损。在年轻和年老沙鼠中收集的间隙检测数据类似于先前发表的来自不同年龄人类的数据，并证实沙鼠是研究时间处理中年龄依赖性变化的有用模型。
