Kwiek Stanisław J, Bierzyńska-Macyszyn Grazyna, Luszawski Jerzy, Właszczuk Paweł, Lewin-Kowalik Joanna, Wolwender Adam, Bazowski Piotr, Wójcikiewicz Tomasz
Department of Neurosurgery, Medical University of Silesia, Katowice, Poland.
Folia Neuropathol. 2003;41(4):237-9.
The objective of the study was to evaluate the dependence of facial nerve paresis, as a symptom of cerebellopontine angle tumour, on the histopathological subtype of vestibular schwannoma, diagnosed from a post-operative histopathological examination. We retrospectively analysed 91 surgically treated patients with vestibular schwannoma. We studied the histopathological subtype and the preoperative condition of the facial nerve. The following WHO 2000 subtypes were distinguished: neurinoma cellular (51 cases), neurinoma conventional (23 cases), neurinoma ancient (11 cases), (other types: 2 neurofibroma and 2 ganglioneuroma). We analysed the dependence of facial nerve paresis on the histological subtype of tumours and their sizes. The analysis was based on the traditional classification: Antoni A (11 cases), Antoni B (12 cases) Antoni A/B (23 cases) and Antoni B/A (40 cases). 30 patients (30%) in the analysed group had paresis of the facial nerve preoperatively. Preoperative facial paresis occurred frequently in subtypes "cellular" and Antoni B, and rarely in subtypes conventional and Antoni A and B/A. In the small tumour cases (up to 20 mm), facial nerve paresis occurred frequently in subtypes cellular and conventional, as well as in Antoni A and A/B.
本研究的目的是评估作为桥小脑角肿瘤症状的面神经麻痹与前庭神经鞘瘤组织病理学亚型之间的相关性,该相关性通过术后组织病理学检查诊断得出。我们回顾性分析了91例接受手术治疗的前庭神经鞘瘤患者。我们研究了组织病理学亚型和术前面神经状况。区分出以下2000年世界卫生组织的亚型:细胞型神经鞘瘤(51例)、传统型神经鞘瘤(23例)、陈旧型神经鞘瘤(11例),(其他类型:2例神经纤维瘤和2例神经节神经瘤)。我们分析了面神经麻痹与肿瘤组织学亚型及其大小之间的相关性。分析基于传统分类:Antoni A(11例)、Antoni B(12例)、Antoni A/B(23例)和Antoni B/A(40例)。分析组中有30例患者(30%)术前存在面神经麻痹。术前面神经麻痹在“细胞型”和Antoni B亚型中频繁出现,而在传统型以及Antoni A和B/A亚型中很少出现。在小肿瘤病例(最大20毫米)中,面神经麻痹在细胞型和传统型亚型以及Antoni A和A/B亚型中频繁出现。