Lanyi Janos K
Department of Physiology and Biophysics, University of California, Irvine, California 92697, USA.
Annu Rev Physiol. 2004;66:665-88. doi: 10.1146/annurev.physiol.66.032102.150049.
Fourier transform infrared and Raman spectroscopy, solid-state NMR, and X-ray crystallography have contributed detailed information about the structural changes in the proton transport cycle of the light-driven pump, bacteriorhodopsin. The results over the past few years add up to a step-by-step description of the configurational changes of the photoisomerized retinal, how these changes result in internal proton transfers and the release of a proton to the extracellular surface and uptake on the other side, as well as the conservation and transformation of excess free energy during the cycle.
傅里叶变换红外光谱和拉曼光谱、固态核磁共振以及X射线晶体学，为光驱动泵细菌视紫红质质子传输循环中的结构变化提供了详细信息。过去几年的研究结果逐步描述了光异构化视黄醛的构型变化，这些变化如何导致内部质子转移以及质子释放到细胞外表面并在另一侧吸收，以及循环过程中多余自由能的守恒和转化。
