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埃塞俄比亚南部达莫特加勒区成年人中的沙眼

Trachoma among adults in Damot Gale District, South Ethiopia.

作者信息

Regassa Kefeyalew, Teshome Tiliksew

机构信息

Department of Ophthalmology, Faculty of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.

出版信息

Ophthalmic Epidemiol. 2004 Feb;11(1):9-16. doi: 10.1076/opep.11.1.9.26440.

Abstract

PURPOSE

To determine the prevalence of trachoma and its risk factors among adults in the Damot Gale District of south Ethiopia.

METHODS

A cross-sectional, community based survey was conducted in the Damot Gale District of south Ethiopia. A multi-stage sampling method was used to select subjects.

RESULTS

Out of 924 eligible subjects, 855 were examined, for a response rate of 92.5%. Active trachoma [follicles (TF), intense inflammation (TI) or TF/TI] was found in 20.6% (95% CI: 17.8-23.4%) of the subjects. The prevalence of trachomatous trichiasis (TT) and corneal opacity (CO) was 6.8% (95% CI: 5.1-8.5%) and 2.1% (95% CI: 1.0-3.1%), respectively. Females were affected by active trachoma twice as often as males [OR 2.13 (95% CI: 1.67-3.50, P<0.0001)]. The prevalence of blinding trachoma (TT and CO) was also significantly higher among females [OR 3.03 (95% CI: 1.58-5.89, P<0.001)]. Literacy and face washing were found to be significantly associated with less prevalence of active trachoma.

CONCLUSION

The prevalence of both active and cicatricial trachoma among adults residing in the Damot Gale District of south Ethiopia is very high. Although children are the main reservoirs of active trachoma, intervention strategies should address the fact that a high prevalence of active trachoma is also found among adults residing in hyperendemic areas.

摘要

目的

确定埃塞俄比亚南部达莫特加勒地区成年人沙眼的患病率及其危险因素。

方法

在埃塞俄比亚南部达莫特加勒地区进行了一项基于社区的横断面调查。采用多阶段抽样方法选取研究对象。

结果

在924名符合条件的研究对象中,855人接受了检查,应答率为92.5%。20.6%(95%可信区间:17.8 - 23.4%)的研究对象患有活动性沙眼[滤泡性沙眼(TF)、重度炎症(TI)或TF/TI]。沙眼性倒睫(TT)和角膜混浊(CO)的患病率分别为6.8%(95%可信区间:5.1 - 8.5%)和2.1%(95%可信区间:1.0 - 3.1%)。女性患活动性沙眼的几率是男性的两倍[比值比2.13(95%可信区间:1.67 - 3.50,P<0.0001)]。致盲性沙眼(TT和CO)在女性中的患病率也显著更高[比值比3.03(95%可信区间:1.58 - 5.89,P<0.001)]。识字和洗脸与活动性沙眼患病率较低显著相关。

结论

居住在埃塞俄比亚南部达莫特加勒地区的成年人中,活动性沙眼和瘢痕性沙眼的患病率都非常高。尽管儿童是活动性沙眼的主要宿主,但干预策略应考虑到在高度流行地区的成年人中也发现了较高的活动性沙眼患病率这一事实。

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