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缅甸农村沙眼相关倒睫和角膜混浊的患病率:眉谬眼科研究

Prevalence of trachoma-related trichiasis and corneal opacity in rural Myanmar: the Meiktila Eye Study.

作者信息

Durkin Shane R, Casson Robert J, Newland Henry S, Aung Than H, Shein Win K, Muecke James S, Selva Dinesh, Aung Than

机构信息

South Australian Institute of Ophthalmology, Adelaide, Australia.

出版信息

Ophthalmology. 2007 May;114(5):e7-11. doi: 10.1016/j.ophtha.2007.01.014.

Abstract

OBJECTIVE

To describe the prevalence of trachomatous trichiasis and corneal opacity (CO) within central Myanmar.

DESIGN

Population-based cross-sectional ophthalmic survey.

PARTICIPANTS

Random, stratified, cluster sampling of the inhabitants > or =40 years of age from villages in the Meiktila District was performed; 2481 eligible participants were identified and 2076 participated in the study.

METHODS

Visual acuity was measured using an E Snellen chart at 6 meters. Lid, ocular surface, and anterior segment examinations were performed at the slit lamp.

MAIN OUTCOME MEASURES

Trachoma was graded as trachomatous trichiasis (TT) or CO according to the World Health Organization grading system.

RESULTS

The population prevalence of trachoma (TT and CO) was 2.6% (95% confidence interval [CI]. 1.67%-3.42%). For every 1-year increase in age, the odds of trachoma increased by 5.3% (95% CI, 4.9%-5.7%). There was no significant effect of gender on the prevalence of trachoma (P = 0.5). No formal schooling was a strong predictor of trachoma (odds ratio, [OR], 4.9; 95% CI, 3.9-6.1), and having <3 children in the house was protective (OR, 0.75; 95% CI, 0.61-0.93); however, neither occupation nor the number of people in a household had an effect on trachoma.

CONCLUSIONS

The prevalence of blinding trachoma in central Myanmar remains relatively low. This is a tribute to the success of the Burma Trachoma Control Program and demonstrates the need for such a program to remain an integral part of public health care and community health services to further diminish the prevalence of this condition. This will be facilitated by a focus on trachoma risk factors and further research into the prevalence of inflammatory trachoma within the pediatric population.

摘要

目的

描述缅甸中部沙眼性倒睫和角膜混浊(CO)的患病率。

设计

基于人群的横断面眼科调查。

参与者

对曼德勒省梅铁拉区村庄中年龄≥40岁的居民进行随机、分层、整群抽样;确定了2481名符合条件的参与者,其中2076人参与了研究。

方法

使用E Snellen视力表在6米处测量视力。在裂隙灯下进行眼睑、眼表和眼前节检查。

主要观察指标

根据世界卫生组织分级系统,将沙眼分级为沙眼性倒睫(TT)或CO。

结果

沙眼(TT和CO)的人群患病率为2.6%(95%置信区间[CI],1.67%-3.42%)。年龄每增加1岁,患沙眼的几率增加5.3%(95%CI,4.9%-5.7%)。性别对沙眼患病率无显著影响(P = 0.5)。未接受正规教育是沙眼的一个强有力预测因素(比值比[OR],4.9;95%CI,3.9-6.1),家中子女<3人具有保护作用(OR,0.75;95%CI,0.61-0.93);然而,职业和家庭人口数量对沙眼均无影响。

结论

缅甸中部致盲性沙眼的患病率仍然相对较低。这归功于缅甸沙眼控制项目的成功,并表明需要该项目继续作为公共卫生保健和社区卫生服务的一个组成部分,以进一步降低这种疾病的患病率。关注沙眼危险因素以及对儿童人群中炎性沙眼患病率的进一步研究将有助于实现这一目标。

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