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睑内翻手术对埃塞俄比亚视力结果的影响。

Effect of trichiasis surgery on visual acuity outcomes in Ethiopia.

作者信息

Woreta Tinsay A, Munoz Beatriz E, Gower Emily W, Alemayehu Wondu, West Sheila K

机构信息

Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21287, USA.

出版信息

Arch Ophthalmol. 2009 Nov;127(11):1505-10. doi: 10.1001/archophthalmol.2009.278.

DOI:10.1001/archophthalmol.2009.278
PMID:19901217
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4700533/
Abstract

OBJECTIVES

To determine the effect of trichiasis surgery on visual acuity.

METHODS

A total of 439 participants in the Surgery for Trichiasis, Antibiotics to Prevent Recurrence (STAR) trial had visual and subjective concerns measured before and 6 months after surgery. Trichiasis surgery was performed in at least 1 eye by integrated eye care workers. Visual acuity was measured using illiterate E versions of Early Treatment Diabetic Retinopathy Study charts with standardized, forced-choice procedures. Improvement was defined as improvement in visual acuity greater than 1 line (5 letters).

RESULTS

The mean improvement in visual acuity for the eyes that had surgery was 0.129 logMAR units (P < .001). Surgery was associated with improvement in visual acuity compared with no surgery (odds ratio, 1.68; 95% confidence interval, 1.04-2.70). Independent predictors of visual acuity improvement in the eyes that had surgery included the number of lashes touching the globe prior to surgery and baseline visual acuity. Among patients, 93.8% described significant pain and 90.4% significant photophobia at baseline compared with only 1.4% and 0.9%, respectively, following surgery.

CONCLUSIONS

Surgery to correct trichiasis appears to provide significant visual acuity improvement as well as a decrease in subjective concerns in patients with trachomatous trichiasis.

TRIAL REGISTRATION

clinicaltrials.gov Identifier: NCT00347776.

摘要

目的

确定倒睫手术对视力的影响。

方法

倒睫手术与抗生素预防复发(STAR)试验中的439名参与者在手术前和术后6个月接受了视力和主观问题测量。综合眼科护理人员至少对一只眼睛进行了倒睫手术。使用早期糖尿病视网膜病变研究图表的文盲E版本,通过标准化的强制选择程序测量视力。视力提高定义为视力提高超过1行(5个字母)。

结果

接受手术的眼睛的平均视力提高为0.129 logMAR单位(P <.001)。与未手术相比,手术与视力提高相关(优势比,1.68;95%置信区间,1.04 - 2.70)。接受手术的眼睛视力提高的独立预测因素包括手术前接触眼球的睫毛数量和基线视力。在患者中,93.8%在基线时描述有明显疼痛,90.4%有明显畏光,而术后分别只有1.4%和0.9%。

结论

矫正倒睫的手术似乎能显著提高沙眼性倒睫患者的视力,并减少主观问题。

试验注册

clinicaltrials.gov标识符:NCT00347776。

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Single-dose azithromycin prevents trichiasis recurrence following surgery: randomized trial in Ethiopia.单剂量阿奇霉素可预防手术后倒睫复发:埃塞俄比亚的随机试验
Arch Ophthalmol. 2006 Mar;124(3):309-14. doi: 10.1001/archopht.124.3.309.
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A randomised controlled trial of azithromycin following surgery for trachomatous trichiasis in the Gambia.在冈比亚针对沙眼性倒睫手术后使用阿奇霉素的一项随机对照试验。
Br J Ophthalmol. 2005 Oct;89(10):1282-8. doi: 10.1136/bjo.2004.062489.
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Long term outcome of trichiasis surgery in the Gambia.冈比亚倒睫手术的长期疗效
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