Gupta A, Patel R, Dyke M
Norfolk and Norwich Univerisity Hospital, Norwich, UK.
Arch Dis Child Fetal Neonatal Ed. 2004 Mar;89(2):F182-3. doi: 10.1136/adc.2002.021147.
Blood banks split an adult packed red cell bag (usually 250 ml) into 30 ml bags, making a total of eight neonatal "satellite" packs per donor. These packs are then "allocated"/"committed" to be used to serially transfuse a newborn.
To study transfusion requirements of premature infants in relation to their birth weight and thereby attempt to rationalise the method of dispensing satellite blood packs.
Data on the distribution of neonatal transfusions with respect to weight were obtained retrospectively from unit A (51 infants, 168 transfusions) and unit B (46 infants, 151 transfusions). These data were used to model the effect of different policies on donor exposure and number of unused packs.
Infants weighing less than 1000 g at birth have significantly higher transfusion requirements than those weighing 1000 g or more (p = 0.001 (unit A), p = 0.004 (unit B)). Our model predicted a significant reduction in donor exposure if eight packs/infant were allocated to those weighing < 1000 g, and a significant cut in the number of unused packs if four satellite packs/infant were allocated to those weighing > or = 1000 g.
It would be safer and cost effective to allocate eight packs/infant to those with birth weights < 1000 g and four packs/infant to those with birth weights > or = 1000 g.
血库将一个成人浓缩红细胞袋（通常为250毫升）分装成30毫升的袋子，每个献血者总共可制成8个新生儿“卫星”血袋。然后这些血袋被“分配”/“指定”用于对一名新生儿进行多次输血。
研究早产儿的输血需求与其出生体重的关系，从而尝试使卫星血袋的分发方法合理化。
回顾性收集了A单位（51例婴儿，168次输血）和B单位（46例婴儿，151次输血）关于新生儿输血按体重分布的数据。这些数据被用于模拟不同政策对献血者暴露情况和未使用血袋数量的影响。
出生体重小于1000克的婴儿输血需求量显著高于体重1000克或以上的婴儿（A单位p = 0.001，B单位p = 0.004）。我们的模型预测，如果为体重<1000克的婴儿分配8个血袋/婴儿，献血者暴露情况将显著减少；如果为体重≥1000克的婴儿分配4个卫星血袋/婴儿，未使用血袋的数量将显著减少。
对于出生体重<1000克的婴儿，分配8个血袋/婴儿；对于出生体重≥1000克的婴儿，分配4个血袋/婴儿，这样做更安全且具有成本效益。
