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小儿大便失禁的病理生理学

Pathophysiology of pediatric fecal incontinence.

作者信息

Di Lorenzo Carlo, Benninga Marc A

机构信息

Division of Pediatric Gastroenterology, Children's Hospital of Pittsburgh, Pennsylvania 15213-7355, USA.

出版信息

Gastroenterology. 2004 Jan;126(1 Suppl 1):S33-40. doi: 10.1053/j.gastro.2003.10.012.

DOI:10.1053/j.gastro.2003.10.012
PMID:14978636
Abstract

This article addresses the diagnosis and treatment of pediatric fecal incontinence in 4 main categories: (1) Functional fecal retention, the withholding of feces because of fear of painful defecation, results in constipation and overflow soiling. Treatment includes dietary changes, use of laxatives, and cognitive and behavioral interventions such as toilet training, which diminishes phobia and provides positive reinforcement through a rewards system. (2) For functional nonretentive fecal soiling (encopresis), antidiarrheal agents can increase the consistency of stools and facilitate continence. Anorectal biofeedback for children has been proposed, but its efficacy remains unproven. Parents should be educated to conduct nonaccusatory toilet training and help children alleviate guilt and enhance self-esteem. Appropriately constructed trials are necessary to gauge the effect of adding prolonged use of enemas to an intensive toilet training program. (3) Surgery can correct minor congenital anorectal anomalies by identifying the external sphincter, separating the rectum from the genitourinary tract, and reconstructing the anus. However, there is great variation in postsurgical functional outcomes for anorectal malformations. Double-blinded, randomized controlled trials could help define the role of appendicostomy, cecostomy, sphincter reconstruction, colostomy, and artificial sphincters. (4) Children with spina bifida and fecal incontinence may benefit from techniques that teach them how to defecate. A continent appendicostomy (Malone procedure) is a promising treatment that completely cleanses the colon, increases the child's autonomy, and decreases the chance of soiling. A cecostomy can be performed surgically, endoscopically, or radiologically to provide some of the same benefits.

摘要

本文从4个主要方面探讨小儿大便失禁的诊断与治疗:(1)功能性粪便潴留,因害怕排便疼痛而憋便,导致便秘和大便失禁。治疗方法包括饮食调整、使用泻药以及认知和行为干预,如排便训练,以减轻恐惧并通过奖励系统给予积极强化。(2)对于功能性无潴留性大便失禁(遗粪症),止泻剂可增加大便稠度并促进控便。已有人提出对儿童进行肛门直肠生物反馈治疗,但其疗效尚未得到证实。应教育家长进行无指责性的排便训练,帮助孩子减轻内疚感并增强自尊心。有必要进行适当设计的试验,以评估在强化排便训练计划中增加长期使用灌肠剂的效果。(3)手术可通过识别外括约肌、将直肠与泌尿生殖道分离并重建肛门来纠正轻微的先天性肛门直肠畸形。然而,肛门直肠畸形术后的功能结果差异很大。双盲随机对照试验有助于明确阑尾造口术、盲肠造口术、括约肌重建术、结肠造口术和人工括约肌的作用。(4)患有脊柱裂和大便失禁的儿童可能受益于教导他们如何排便的技术。可控性阑尾造口术(马龙手术)是一种有前景的治疗方法,可彻底清洁结肠,增加患儿的自主性,并减少大便失禁的几率。盲肠造口术可通过手术、内镜或放射学方法进行,以提供一些相同的益处。

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