Di Lorenzo L, Cassano F, Elia G, Gagliardi T, Silvestroni A, Lovreglio P, Corfiati M, Soleo L
Dipartimento di Medicina Interna e di Medicina Pubblica, Sezione di Medicina del Lavoro, Università degli Studi di Bari.
G Ital Med Lav Ergon. 2003 Jul-Sep;25 Suppl(3):114-5.
The aim of this study is to evaluate the effects of occupational exposure to low inorganic lead (Pb) doses on blood pressure of exposed (E) workers. 44 workers of a foundry of lead wrecks and 14 workers employed in enameling and decoration of a manufacturing firm of artistic ceramics were examined. The group of non-exposed (NE) subjects is formed by 59 workers of packaging unit of a food industry. A questionnaire has been administered to all the workers on general characteristics and life habits. Systolic and diastolic blood pressure were also measured and venous blood collection performed for the determination of blood lead levels. Mean blood lead levels (PbB) and mean diastolic blood pressure (DBP) resulted significantly higher in the group of exposed workers of the foundry. Stratifing exposed workers with respect to the median of PbB (18 micrograms/dl), workers with PbB > 18 micrograms/dl presented a mean DBP significantly higher than exposed with PbB < or = 18 micrograms/dl and non-exposed subjects. PbB takes part significantly in determination of DBP, also considering main confounding factors as age, BMI, pack-years and alcohol consumption.
本研究的目的是评估职业性接触低剂量无机铅（Pb）对接触铅（E）工人血压的影响。对一家铅制品铸造厂的44名工人以及一家艺术陶瓷制造公司从事搪瓷和装饰工作的14名工人进行了检查。非接触（NE）组由一家食品工业包装部门的59名工人组成。已向所有工人发放了一份关于一般特征和生活习惯的问卷。还测量了收缩压和舒张压，并采集静脉血以测定血铅水平。铸造厂接触铅工人组的平均血铅水平（PbB）和平均舒张压（DBP）显著更高。根据PbB中位数（18微克/分升）对接触铅工人进行分层，PbB>18微克/分升的工人的平均DBP显著高于PbB≤18微克/分升的接触铅工人和非接触组。考虑到年龄、体重指数、吸烟包年数和酒精摄入量等主要混杂因素，PbB在DBP的测定中也有显著作用。
