Ikebe T, Murayama S, Saitoh K, Yamai S, Suzuki R, Isobe J, Tanaka D, Katsukawa C, Tamaru A, Katayama A, Fujinaga Y, Hoashi K, Watanabe H
Department of Bacteriology, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
Epidemiol Infect. 2004 Jan;132(1):145-9. doi: 10.1017/s0950268803001262.
The number of patients with severe invasive group-G streptococcal (Streptococcus dysgalactiae subsp. equisimilis) infections has been increasing in Japan. The emm genotypes and SmaI-digested pulsed-field gel electrophoresis DNA profiles were variable among the strains isolated, suggesting there has not been clonal expansion of a specific subpopulation of strains. However, all strains carried scpA, ska, slo and sag genes, some of which may be involved in the pathogenesis of the disease.
在日本，严重侵袭性G群链球菌（马链球菌兽疫亚种）感染患者的数量一直在增加。在分离出的菌株中，emm基因型和经SmaI酶切的脉冲场凝胶电泳DNA图谱各不相同，这表明没有特定菌株亚群的克隆性扩增。然而，所有菌株都携带scpA、ska、slo和sag基因，其中一些基因可能与该疾病的发病机制有关。
