Jourani M, Duprez T, Roelants V, Rodriguez-Villalobos H, Hantson P
Department of Intensive Care, Cliniques St-Luc, Université Catholique de Louvain, Brussels, Belgium.
Department of Radiology, Neuroradiology Division, Cliniques St-Luc, Université Catholique de Louvain, Brussels, Belgium.
Case Rep Infect Dis. 2017;2017:8645859. doi: 10.1155/2017/8645859. Epub 2017 Apr 23.
Disseminated abscesses due to group G -hemolytic were observed in a 57-year-old cirrhotic patient with the skin being the putative way of entry for the pathogen. is a rare agent in human infections responsible for acute pyogenic meningitis. The mortality rate associated with bacteraemia and meningitis may be as high as 50%, particularly in the presence of endocarditis or brain abscesses. In our patient, main sites of infections were meningitis and ventriculitis, spondylodiscitis, septic arthritis, and soft-tissue infections. In contrast, no endocarditis was evidenced. Cirrhosis-related immune suppression was considered as a pathophysiological cofactor for the condition. Fortunately, clinical status improved after long-term (3 months) antimicrobial therapy.
在一名57岁的肝硬化患者中观察到由G组溶血性链球菌引起的播散性脓肿，皮肤被认为是病原体的侵入途径。 是人类感染中导致急性化脓性脑膜炎的罕见病原体。与 菌血症和脑膜炎相关的死亡率可能高达50%，特别是在存在心内膜炎或脑脓肿的情况下。在我们的患者中，主要感染部位是脑膜炎和脑室炎、脊椎间盘炎、化脓性关节炎和软组织感染。相比之下，未发现心内膜炎。肝硬化相关的免疫抑制被认为是该病症的病理生理辅助因素。幸运的是，经过长期（3个月）抗菌治疗后临床状况有所改善。
