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亚种感染所致急性细菌性脑膜炎和全身性脓肿

Acute Bacterial Meningitis and Systemic Abscesses due to subsp. Infection.

作者信息

Jourani M, Duprez T, Roelants V, Rodriguez-Villalobos H, Hantson P

机构信息

Department of Intensive Care, Cliniques St-Luc, Université Catholique de Louvain, Brussels, Belgium.

Department of Radiology, Neuroradiology Division, Cliniques St-Luc, Université Catholique de Louvain, Brussels, Belgium.

出版信息

Case Rep Infect Dis. 2017;2017:8645859. doi: 10.1155/2017/8645859. Epub 2017 Apr 23.

Abstract

Disseminated abscesses due to group G -hemolytic were observed in a 57-year-old cirrhotic patient with the skin being the putative way of entry for the pathogen. is a rare agent in human infections responsible for acute pyogenic meningitis. The mortality rate associated with bacteraemia and meningitis may be as high as 50%, particularly in the presence of endocarditis or brain abscesses. In our patient, main sites of infections were meningitis and ventriculitis, spondylodiscitis, septic arthritis, and soft-tissue infections. In contrast, no endocarditis was evidenced. Cirrhosis-related immune suppression was considered as a pathophysiological cofactor for the condition. Fortunately, clinical status improved after long-term (3 months) antimicrobial therapy.

摘要

在一名57岁的肝硬化患者中观察到由G组溶血性链球菌引起的播散性脓肿,皮肤被认为是病原体的侵入途径。 是人类感染中导致急性化脓性脑膜炎的罕见病原体。与 菌血症和脑膜炎相关的死亡率可能高达50%,特别是在存在心内膜炎或脑脓肿的情况下。在我们的患者中,主要感染部位是脑膜炎和脑室炎、脊椎间盘炎、化脓性关节炎和软组织感染。相比之下,未发现心内膜炎。肝硬化相关的免疫抑制被认为是该病症的病理生理辅助因素。幸运的是,经过长期(3个月)抗菌治疗后临床状况有所改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1151/5420411/3d7f3912f3d7/CRIID2017-8645859.001.jpg

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